[1] Johns Hopkins University. Coronavirus Resource Center. Available from: https://coronavirus.jhu.edu/ map.html (accessed on February12, 2021)
[2] (https://covid19.who.int/region/emro/country/ir).
[3] Karimi J. Epidemiological review of the coronavirus disease 2019 (COVID-19) pandemic up to 15 March 2020. Journal of Isfahan Medical School. 2020;38(561):14-23.
[4] Guy RK, DiPaola RS, Romanelli F, Dutch RE. Rapid repurposing of drugs for COVID-19. Science. 2020 May 22;368(6493):829-30. [10.1126/science.abb9332 ][PMID]
[5] Kausar S, Said Khan F, Ishaq Mujeeb Ur Rehman M, Akram M, Riaz M, Rasool G, Hamid Khan A, Saleem I, Shamim S, Malik A. A review: Mechanism of action of antiviral drugs. International journal of immunopathology and pharmacology. 2021 Mar;35:20587384211002621.[10.1177/20587384211002621][PMID]
[6] Akdis CA, Simons FE. Histamine receptors are hot in immunopharmacology. European journal of pharmacology. 2006 Mar 8;533(1-3):69-76.[10.1016/j.ejphar.2005.12. 044][PMID]
[7] Ge S, Lu J, Hou Y, Lv Y, Wang C, He H. Azelastine inhibits viropexis of SARS-CoV-2 spike pseudovirus by binding to SARS-CoV-2 entry receptor ACE2. Virology. 2021 Aug 1;560:110-5.[ 10.1016/j.virol.2021.05.009 ][PMID]
[8] Hou Y, Ge S, Li X, Wang C, He H, He L. Testing of the inhibitory effects of loratadine and desloratadine on SARS-CoV-2 spike pseudotyped virus viropexis. Chemico-biological interactions. 2021 Apr 1;338:109420.[ 10.1016/j.cbi.2021.109420 ][PMID]
[9] Ge S, Wang X, Hou Y, Lv Y, Wang C, He H. Repositioning of histamine H1 receptor antagonist: Doxepin inhibits viropexis of SARS-CoV-2 Spike pseudovirus by blocking ACE2. European Journal of Pharmacology. 2021 Apr 5;896:173897.[10.1016/ j.ejphar.2021.173897 ][PMID]
[10] Yang L, Pei RJ, Li H, Ma XN, Zhou Y, Zhu FH, He PL, Tang W, Zhang YC, Xiong J, Xiao SQ. Identification of SARS-CoV-2 entry inhibitors among already approved drugs. Acta Pharmacologica Sinica. 2021 Aug;42(8):1347-53. [10.1038/s41401-020-00556-6 ][PMID]
[11] Moher D, Liberati A, Tetzlaff J, Altman DG, PRISMA Group*. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Annals of internal medicine. 2009 Aug 18;151(4):264-9. [10.1016/j.ijsu.2010.02.007 ][PMID]
[12] Higgins JP. Cochrane handbook for systematic reviews of interventions version 5.0. 1. The Cochrane Collaboration. http://www. cochrane-handbook. org. 2008. [Link]
[13] Ennis M, Tiligada K. Histamine receptors and COVID-19. Inflammation Research. 2021 Jan;70:67-75. [10.1007/s00011-020-01422-1 ][PMID]
[14] May BC, Gallivan KH. Levocetirizine and montelukast in the COVID-19 treatment paradigm. International Immunopharmacology. 2022 Feb 1;103:108412. [10.1016/j.intimp.2021.108412 ][PMID]
[15] Reznikov LR, Norris MH, Vashisht R, Bluhm AP, Li D, Liao YS, Brown A, Butte AJ, Ostrov DA. Identification of antiviral antihistamines for COVID-19 repurposing. Biochemical and biophysical research communications. 2021 Jan 29;538:173-9. doi: 10.1016/j.bbrc.2020.11.095. Epub 2020 Dec 3. PMID:
33309272; PMCID: PMC7713548. [10.1016/j.bbrc.2020.11. 095][PMID]
[16] Morán Blanco JI, Alvarenga Bonilla JA, Homma S, Suzuki K, Fremont-Smith P, Villar Gómez de las Heras K. Antihistamines and azithromycin as a treatment for COVID-19 on primary health care-A retrospective observational study in elderly patients. Pulm Pharmacol Ther. 2021:101989-. [10.1016/j. pupt.2021.101989][PMID]
[17] Chiu L, Shen M, Lo CH, Chiu N, Chen A, Shin HJ, Prsic EH, Hur C, Chow R, Lebwohl B. Effect of famotidine on hospitalized patients with COVID-19: A systematic review and meta-analysis. PLoS One. 2021 Nov 4;16(11):e0259514. [10.1371/ journal.pone.0259514 ][PMID]
[18] Janowitz T, Gablenz E, Pattinson D, Wang TC, Conigliaro J, Tracey K, Tuveson D. Famotidine use and quantitative symptom tracking for COVID-19 in non-hospitalised patients: a case series. Gut. 2020 Sep 1;69(9):1592-7. doi: 10.1136/gutjnl-2020-321852. Epub 2020 Jun 4. PMID: 32499303; PMCID: PMC7299656. [10.1136/gutjnl-2020-321852 ][PMID]
[19] Ge S, Wang X, Hou Y, Lv Y, Wang C, He H. Repositioning of histamine H1 receptor antagonist: Doxepin inhibits viropexis of SARS-CoV-2 Spike pseudovirus by blocking ACE2. European Journal of Pharmacology. 2021 Apr 5;896:173897. [10.1136/ gutjnl-2020-321852 ][PMID]
[20] Mather JF, Seip RL, McKay RG. Impact of Famotidine Use on Clinical Outcomes of Hospitalized Patients With COVID-19. Am J Gastroenterol. 2020 Oct;115(10):1617-1623. [10.14309/ajg.0000000000000832 ][PMID]
[21] Qu C, Fuhler GM, Pan Y. Could histamine H1 receptor antagonists be used for treating COVID-19?. International Journal of Molecular Sciences. 2021 May 26;22(11):5672. [10.3390/ijms22115672 ][PMID]
[22] Kuno T, So M, Takahashi M, Egorova NN. The association between famotidine and in‐hospital mortality of patients with COVID‐19. Journal of Medical Virology. 2022 Mar;94(3):1186-9. [10.1002/jmv.27375 ][PMID]
[23] Eldanasory OA, Eljaaly K, Memish ZA, Al-Tawfiq JA. Histamine release theory and roles of antihistamine in the treatment of cytokines storm of COVID-19. Travel medicine and infectious disease. 2020 Sep;37:101874. [10.1016/j.tmaid.2020.101874 ][PMID]
[24] Brennan CM, Nadella S, Zhao X, Dima RJ, Jordan-Martin N, Demestichas BR, Kleeman SO, Ferrer M, von Gablenz EC, Mourikis N, Rubin ME. Oral famotidine versus placebo in non-hospitalised patients with COVID-19: a randomised, double-blind, data-intense, phase 2 clinical trial. Gut. 2022 May 1;71(5):879-88. [10.1136/gutjnl-2022-326952 ][PMID]
[25] Hou Y, Ge S, Li X, Wang C, He H, He L. Testing of the inhibitory effects of loratadine and desloratadine on SARS-CoV-2 spike pseudotyped virus viropexis. Chemico-biological interactions. 2021 Apr 1;338:109420. [10.1016/j.cbi.2021.109420 ][PMID]
[26] Cheung KS, Hung IF, Leung WK. Association between famotidine use and COVID-19 severity in Hong Kong: a territory-wide study. Gastroenterology. 2020; S0016–5085. (20)34940-4. doi: 10.1053/j. gastro.2020.05.098. [10.1053/j.gastro.2020.05.098 ][PMID]
[27] Zhou J, Wang X, Lee S, Wu WK, Cheung BM, Zhang Q, Tse G. Proton pump inhibitor or famotidine use and severe COVID-19 disease: a propensity score-matched territory-
Jundishapur
Journal of Medical Sciences
January & February 2024. Vol 22. No 6
Momen T, et al. Antihistamines in COVID-19 Symptoms. JSMJ. 2024; 22(6):767-777
777
wide study. Gut. 2021 Oct 1;70(10):2012-3. [10.1136/ gutjnl-2020-323668][PMID]
[28] Sánchez-Rico M, Limosin F, Vernet R, Beeker N, Neuraz A, Blanco C, Olfson M, Lemogne C, Meneton P, Daniel C, Paris N. Hydroxyzine use and mortality in patients hospitalized for COVID-19: a multicenter observational study. Journal of Clinical Medicine. 2021 Dec 15;10(24):5891. [10.3390/ jcm10245891][PMID]
[29] Oh KK, Adnan M, Cho DH. Network pharmacology approach to decipher signaling pathways associated with target proteins of NSAIDs against COVID-19. Scientific reports. 2021 May 5;11(1):9606. [Link]
[30] Antiviral Potential of Azelastine against Major Respiratory Viruses. Fischhuber K, Bánki Z, Kimpel J, Kragl N, Rössler A, Bolze A, Muellauer B, Angerer J, Nagy G, Nagy E, Szijarto V. Viruses. 2023 Nov 23;15(12):2300. [10.3390/v15122300 ][PMID]
)