[1] Genco RJ. Current view of risk factors for periodontal diseases.
J Periodontol. 1996; 67(S 10):1041-9. [DOI:10.1902/
jop.1996.67.10.1041]
[2] Pihlstrom BL, Michalowicz BS, Johnson NW. Periodontal diseases.
lancet. 2005; 366(9499):1809-20. [DOI:10.1016/S0140-
6736(05)67728-8]
[3] Piscoya M, Ximenes R, Silva G, Jamelli S, Coutinho S. Periodontitis-
associated risk factors in pregnant women. Clinics. 2012;
67(1):27-33. [DOI:10.6061/clinics/2012(01)05]
[4] Loesche WJ, Grossman NS. Periodontal disease as a specific,
albeit chronic, infection: Diagnosis and treatment. Clin Microbiol
Rev. 2001; 14(4):727-52. [DOI:10.1128/CMR.14.4.727-
752.2001] [PMID] [PMCID]
[5] Zini A, Sgan-Cohen HD, Marcenes W. Socio-economic position,
smoking, and plaque: A pathway to severe chronic periodontitis.
J Clin Periodontol. 2011; 38(3):229-35. [DOI:10.1111/
j.1600-051X.2010.01689.x] [PMID]
[6] Borrell LN, Papapanou PN. Analytical epidemiology of
periodontitis. J Clin Periodontol. 2005; 32(S 6):132-58.
[DOI:10.1111/j.1600-051X.2005.00799.x] [PMID]
[7] Petersen PE, Bourgeois D, Ogawa H, Estupinan-Day S, Ndiaye
C. The global burden of oral diseases and risks to oral health.
Bull World Health Organ. 2005; 83(9):661-9. [PMCID]
[8] Zhang HY, Feng L, Wu H, Xie XD. The association of IL‐6 and
IL‐6R gene polymorphisms with chronic periodontitis in a Chinese
population. Oral Dis. 2014; 20(1):69-75. [DOI:10.1111/
odi.12075] [PMID]
[9] Miller CS, Foley JD, Bailey AL, Campell CL, Humphries RL,
Christodoulides N, et al. Current developments in salivary
diagnostics. Biomark Med. 2010; 4(1):171-89. [DOI:10.2217/
bmm.09.68] [PMID] [PMCID]
[10] Miller CS, King Jr CP, Langub MC, Kryscio RJ, Thomas MV.
Salivary biomarkers of existing periodontal disease: A crosssectional
study. J Am Dent Assoc. 2006; 137(3):322-9.
[DOI:10.14219/jada.archive.2006.0181] [PMID]
[11] Miricescu D, Greabu M, Totan A, Didilescu A, Rădulescu R.
The antioxidant potential of saliva: Clinical significance in oral
diseases. Ther Pharmacol Clin Toxicol. 2011; 15(2):139-43. https://
www.researchgate.net/publication/267037016_The_antioxidant_
potential_of_saliva_Clinical_significance_in_oral_
diseases
[12] Nagler RM, Klein I, Zarzhevsky N, Drigues N, Reznick AZ. Characterization
of the differentiated antioxidant profile of human
saliva. Free Radic Biol Med. 2002; 32(3):268-77. [DOI:10.1016/
S0891-5849(01)00806-1]
[13] Steinberg BJ, Hilton IV, Iida H, Samelson R. Oral health and
dental care during pregnancy. Dent Clin North Am. 2013;
57(2):195-210. [DOI:10.1016/j.cden.2013.01.002] [PMID]
[14] Laine MA. Effect of pregnancy on periodontal and dental
health. Acta Odontol Scand. 2002; 60(5):257-64.
[DOI:10.1080/00016350260248210] [PMID]
[15] Scannapieco FA, Bush RB, Paju S. Periodontal disease as a
risk factor for adverse pregnancy outcomes. A systematic
review. Ann Periodontol. 2003; 8(1):70-8. [DOI:10.1902/annals.
2003.8.1.70] [PMID]
[16] Rakoto-Alson S, Tenenbaum H, Davideau JL. Periodontal diseases,
preterm births, and low birth weight: Findings from a
homogeneous cohort of women in Madagascar. J Periodontol.
2010; 81(2):205-13. [DOI:10.1902/jop.2009.090351] [PMID]
[17] Komine-Aizawa S, Aizawa S, Hayakawa S. Periodontal diseases
and adverse pregnancy outcomes. J Obstet Gynaecol Res.
2019; 45(1):5-12. [DOI:10.1111/jog.13782] [PMID]
[18] Armitage GC. Periodontal diagnoses and classification
of periodontal diseases. Periodontol 2000. 2004; 34:9-21.
[DOI:10.1046/j.0906-6713.2002.003421.x]
[19] Navazesh M. Methods for collecting saliva. Ann N Y Acad Sci.
1993; 694:72-7. [DOI:10.1111/j.1749-6632.1993.tb18343.x]
[PMID]
[20] Eke PI, Dye BA, Wei L, Slade GD, Thornton‐Evans GO, Borgnakke
WS, et al. Update on prevalence of periodontitis in adults
in the United States: NHANES 2009 to 2012. J Periodontol.
2015; 86(5):611-22. [DOI:10.1902/jop.2015.140520] [PMID]
[PMCID]
[21] Rathnayake N, Åkerman S, Klinge B, Lundegren N, Jansson
H, Tryselius Y, et al. Salivary biomarkers of oral health-a
cross‐sectional study. J Clin Periodontol. 2013; 40(2):140-7.
[DOI:10.1111/jcpe.12038] [PMID]
[22] Geng W-y, Ying-Hui T, Sheng-Gen S. Expression of IL-6 and
TNF-α activities in saliva of chronic periodontitic patients. Chin
J Conserv Dent. 2009; 5:11. https://en.cnki.com.cn/Article_
en/CJFDTotal-YTYS200905011.htm
[23] Teles R, Likhari V, Socransky S, Haffajee A. Salivary cytokine
levels in subjects with chronic periodontitis and in
periodontally healthy individuals: A cross‐sectional study. J
Periodontal Res. 2009; 44(3):411-7. [DOI:10.1111/j.1600-
0765.2008.01119.x] [PMID] [PMCID]
[24] Elshal MF, McCoy JP. Multiplex bead array assays: Performance
evaluation and comparison of sensitivity to
ELISA. Methods. 2006; 38(4):317-23. [DOI:10.1016/j.ymeth.
2005.11.010] [PMID] [PMCID]
[25] Keles Yucel ZP, Keles GC, Avci B, Cetinkaya BO. Nonsurgical
periodontal therapy reduces salivary and gingival Crevicular
Fluid YKL-40 and IL-6 Levels in Chronic Periodontitis. Oral
Health Prev Dent. 2020; 18(1):815-22. [DOI:10.3290/j.ohpd.
a45086]
[26] Kc S, Wang XZ, Gallagher JE. Diagnostic sensitivity and specificity
of host-derived salivary biomarkers in periodontal disease
amongst adults: Systematic review. J Clin Periodontol.
2020; 47(3):289-308. [DOI:10.1111/jcpe.13218] [PMID]
[27] Machado V, Mesquita MF, Bernardo MA, Casal E, Proença L,
Mendes JJ. IL-6 and TNF-α salivary levels according to the periodontal
status in Portuguese pregnant women. PeerJ. 2018;
6:e4710. [DOI:10.7717/peerj.4710] [PMID] [PMCID]
[28] Page RC, Offenbacher S, Schroeder HE, Seymour GJ, Kornman
KS. Advances in the pathogenesis of periodonti-
Yousefimanesh H, et al. Evaluation of Salivary IL-6 Correlation Between Pregnancy and Periodontal Disease. JSMJ. 2022; 20(SpecialIssue):690-697
696
Fّeb, Mar 2022. Volume 20. Number 6
tis: Summary of developments, clinical implications and
future directions. Periodontol 2000. 1997; 14:216-48.
[DOI:10.1111/j.1600-0757.1997.tb00199.x] [PMID]
[29] Huck O, Tenenbaum H, Davideau JL. Relationship between
periodontal diseases and preterm birth: Recent epidemiological
and biological data. J Pregnancy. 2011; 2011:164654.
[DOI:10.1155/2011/164654] [PMID] [PMCID]
)