Morphea of the breast is an uncommon clinical disease and may have profound effects on the quality life of the patients. The disease can also mimic inflammatory benign and malignant diseases of the breast and differentiation between them is sometimes very difficult.
Herein, we report a case of morphea of the breast in a 28-year- old female with a history of skin changes of the right breast who referred to a general surgeon for possible diagnosis and treatment of the breast cancer. Diagnosis of the breast morphea with skin biopsy was proven after one year. We describe morphea of the breast and discuss our experience on the differentiation of the morphea of the breast with inflammatory breast cancer.