The Effect of Resistance Training on Anthropometric Characteristics and Lipid Profile in Men with Type 2 Diabetes Referred to Golestan Hospital

Document Type : Original Article


1 Department of Sport Physiology, School of Sport, Shahid Chamran University, Ahvaz , Iran.

2 Health Research Institute, Diabetes Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.


Background and Objective: Physical activity is one of the most important factors in diabetes treatment. The purpose of this study was to investigate the effect of resistance training on anthropometric status and lipid profile in men with type 2 diabetes.  
Subjects and Methods: Twenty patients with type 2 diabetes (age: 46±3.4) and Fasting plasma glucose [(FPG) 148.75±31.5 mg/dl] participated in this semi-experimental study. The subjects were randomly divided into two groups, resistance training group (n=10) and control group (n=10). Exercise training program was performed for 8 weeks with 3 sessions per week. FPG, Lipid profile and anthropometric indices [waist to hip ratio (WHR), Percentage of body fat (PBF) /WHR index] were measured before and after the intervention. Statistical analysis was carried out using independent T-test, at significance level of P<0.05.
Results: At the end of the training period, resistance training produced significant decrease in WHR (P=0.021) and a significant increase HDL (P=0.039). In addition, it was observed significant differences between 2 groups in PBF% (P=0.048) and WHR (P=0.039).
Conclusions: It appears that resistance training improves body composition and increases HDL in men with type 2 diabetes.


1-Wang C, Guan Y, Yang J. Cytokines in the progression of pancreatic β-Cell dysfunction. Int j endol 2010; 2010 Oct. Article ID 515136, doi:10.1155/2010/515136.
2-American diabetes association: Report of the expert committee on diagnosis and classification of diabetes mellitus. Diabetes Care 1997; 20: 1183-97.
3-Garcia MJ, McNamara PM, Gordon T, Kannel WB. Morbidity and mortality in diabetics in Framingham population: Sixteen year follow- up study. Diabetes 1974; 23(2):105-11.
4-American diabetes association: Role of cardiovascular risk factors in prevention and treatment of macrovascular disease in diabetes. Diabetes Care 1989 Sep;12(8): 573-9.
5-Safaei H, Amini M, Behroz J. Cardiovascular risk Factors in patiots with newly diagnosed Type 2 diabetes. Iranian Jornal of Endocrinology& Metabolism 2006; 8(1): 31-8.
6-Stewart KJ. Exercise training: can it improve cardiovascular health in patients with type 2 diabetes? Br J SportsMed 2004 Jun; 38(3): 250- 2.
7-Chinikar M, Maddah M, Hoda S. Coronary artery disease in Iranian overweight women. International journal of cardiology 2006; 113(3): 391-4.
8-Tadibi V, Bayat Z. The Effectiveness of 8-week aerobic exercise and drug modification on metabolic indices in women with type 2 diabetes. Journal of Kermanshah University of Medical Sciences 2012; 16(5): 380-90.
9-Martinus R, Corban R, Wackerhage H, Atkins S, Singh J. Effect of psychological intervention on exercise adherence in type 2 diabetic subjects. Annals of the New York Academy of Sciences 2006; 1084(1): 350-60.
10-Mohebi H, Khazaei MH, Esfahani M. Effects of Aerobic Exercise Traning on glysemic control, cardio-respiratory fotness, and associated cardiovascular risk factors in patients with mild and severe NIDDM. OLYMPIC 2007; 4(13): 17-24.
11-Shavandi N, SHAHRJERDI S, Sheikh Hoseini R, Ghorbani A. The Effect of Strengthening Exercises on Metabolic Factors, Quality of Life and Mental Health in Women With Type 2 Diabetes. IJEM 2010; 12(3): 222-30.
12-Hashemi javaheri SAA, Saberi M, Mohamad Rahimi N, Khodaei M. Body Mass INDEX, Waist to Hip Ratio, and Percentage of Body Fat of the chemical war survivors in razavi Khorasan. TEBE-E-JANBAZ 2012; 4(14): 34-40.
13-Vickers KS, Nies MA, Patten CA, Dierkhising R, Smith SA. Patients with diabetes and depression may need additional support for exercise. Am J Health Behav 2006; 30(4): 353-62.
14-Yassine HN, Marchetti CM, Krishnan RK, Vrobel TR, Gonzalez F, Kirwan JP. Effects of exercise and caloric restriction on insulin resistance and cardiometabolic risk factors in older obese adults—a randomized clinical trial. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences 2009; 64(1): 90-5.
15-Friedewald WT, Levy RI, Fredrickson DS. Estimationof the Concentrationof Low-Density LipoproteinCholesterolin Plasma,Without Useof the PreparativeUltracentrifuge. CLINICAL CHEMISTRY 1972; 18(6): 499- 502.
16-Yavari A, Najafipoor F, Aliasgarzadeh A, Niafar M, Mobasseri M. Effect of Aerobic Exercise, Resistance Traning or Combined Traning on glycemic control and cardio- vascular risk factor in patients withType 2 Diabetes. Biol Sport 2012; 29(2):135-43.
17-Hoffman j. Norms for fitness, performance and health. USA: Human Kinetics; 2006. P. 30- 52.
18-Egger A, Niederseer D, Diem G, Finkenzeller T, Kurkowski EL, Forstner R, "et al". Different types of resistance training in patients with type 2 diabetes mellitus: effects on glycemic control, muscle mass and strength European. Journal of Preventive Cardiology 2012:1-10. DOI: 10.1177/2047487312450132.
19-Misra A, Alappan NK, Vikram NK, Goel K, Gupta N, Mittal K, "et al". Effect of Supervised Progressive Resistance-Exercise Training Protocol on Insulin Sensitivity, Glycemia, Lipids, and Body Composition in Asian Indians With Type 2 Diabetes. Diabetes Care 2008; 31(7): 1282-7.
20-Ibanez J, Izquierdo M, Arguelles I, Forga L, Larrion JL. Twice-Weekly Progressive Resistance Training Decreases Abdominal Fat and Improves Insulin Sensitivity in Older Men With Type 2 Diabetes. Diabetes Care 2005; 28: 662–7.
21-De Feyter HM, Praet SF, van den Broek NM, Kuipers H, Stehouwer CD, Nicolay K, "et al". Exercise training improves glycemic control in long-standing insulin-treated type 2 diabetic patients. Diabetes Care 2007; 30(10): 2511-3.
22-Eizadi M, Karimi M, Kohandel M, Duali H. Effect of aerobic exercise on serum leptin response and insulin resistance of patients with type 2 diabetes. JQUMS 2013;16(4): 33-9.
23-Cuff DJ, Meneilly GS, Martin A, Ignaszewski A, Tildesley HD, Frohlich JJ. Effective exercise modality to reduce insulin resistance in women with type 2 diabetes. Diabetes care 2003; 26(11): 2977-82.
24-Moran LJ, Noakes M, Clifton PM, Tomlinson L, Norman RJ. Dietary composition in restoring reproductive and metabolic physiology in overweight women with polycystic ovary syndrome. Journal of Clinical Endocrinology & Metabolism 2003; 88(2): 812-9.
25-Huber-Buchholz M-M, Carey D, Norman RJ. Restoration of reproductive potential by lifestyle modification in obese polycystic ovary syndrome: role of insulin sensitivity and luteinizing hormone. Journal of Clinical Endocrinology & Metabolism 1999; 84(4): 1470-4.
26-Thomson RL, Buckley JD, Noakes M, Clifton PM, Norman RJ, Brinkworth GD. The effect of a hypocaloric diet with and without exercise training on body composition, cardiometabolic risk profile, and reproductive function in overweight and obese women with polycystic ovary syndrome. Journal of Clinical Endocrinology & Metabolism 2008 Sep;93(9):3373-80.
27-Bahrami A, Saremi A. Effect of caloric restriction with or without aerobic training on body composition, blood lipid profile, insulin resistance, and inflammatory marker in middle-age obese/overweight men. Arak Medical University Journal 2011;14(3):11-9.
28-Gabriely I, Ma XH, Yang XM, Atzmon G, Rajala MW, Berg AH. Removal of visceral fat prevents insulin resistance and glucose intolerance of aging: an adipokine-mediated process. Diabetes 2002 Oct; 51(10): 2951-8.
29-Hays NP, Starling RD, Sullivan DH, D FJ, RH C, Williams RH. Effects of an ad libitum, high carbohydrate diet and aerobic exercise training on insulin action and muscle metabolism in older men and women. J Gerontol A Biol Sci Med Sci 2006 Mar; 61(3):299-304.
30-Hays NP, Starling RD, Sullivan DH, Fluckey JD, Coker RH, Evans WJ. Comparison of insulin sensitivity assessment indices with euglycemic-hyperinsulinemic clamp data after a dietary and exercise intervention in older adults. Metabolism 2006 Apr;55(4):525-32.
31-Albright A, Franz M, Hornsby G, Kiriska A, Marrero D, Urlich I. Exercise and type diabetes. Med Sci Sports Med 2000; 32(7): 1345-60.
32-Bacchi E, Negri C, Zanolin ME, Milanese C, Faccioli N, Trombetta M, "et al". Metabolic Effects of Aerobic Training and Resistance Training in Type 2 Diabetic Subjects A randomized controlled trial (the RAED2 study). Diabetes care 2012 Apr; 35(4): 676-82.
33-Castaneda C, Layne JE, Munoz-Orians L, Gordon PL, Walsmith J, Foldvari M, "et al". A randomized controlled trial of resistance exercise training to improve glycemic control in older adults with type 2 diabetes. Diabetes care 2002; 25(12): 2335-41.
34-Alam S, Stolinski M, Pentecost C, Boroujerdi MA, Jones RH, Sonksen PH, "et al". The effect of a six-month exercise program on very low-density lipoprotein apolipoprotein B secretion in type 2 diabetes. Journal of Clinical Endocrinology & Metabolism 2004; 89(2): 688-94.
35-Plotnikoff R, Courneya K, Trinh L, Karunamuni N, Sigal R. Aerobic physical activity and resistance training: an application of the theory of planned behavior among adults with type 2 diabetes in a random, national sample of Canadians. Int J Behav Nutr Phys Act 2008; 5(61):1-14.
36-Ferguson MA, Alderson NL, Trost SG, Essig DA, Burke JR, Durstine JL. Effects of four different single exercise sessions on lipids, lipoproteins, and lipoprotein lipase. Journal of applied Physiology 1998; 85(3):1169-74.
37-Kantor MA, Cullinane EM, Sady SP, Herbert PN, Thompson PD. Exercise acutely increases high density lipoprotein cholesterol and lipoprotein lipase activity in trained and untrained men. Metabolism1987 Feb;86(2):188–92.
38-Van Gaal L, Rillaerts E, Creten W, De Leeuw I. Relationship of body fat distribution pattern to atherogenic risk factors in NIDDM: preliminary results. Diabetes Care 1988 Feb; 11(2):103-6.
39-Després J-P, Moorjani S, Tremblay A, Poehlman ET, Lupien PJ, Nadeau A, "et al". Heredity and changes in plasma lipids and lipoproteins after short-term exercise training in men. Arteriosclerosis, Thrombosis, and Vascular Biology 1998 Jul-Aug;8(4):402-9.
40-Hawley JA, Zierath JR. Physical Activity and Type 2 Diabetes: Therapeutic Effects and Mechanisms of Action. USA: Human Kinetics; 2008.