Prevalence of Cardiovascular Risk factors in Diabetic Patients Attending to Ahvaz Golestan Hospital

Document Type : Original Article


1 Department of Endocrinology, Health Research Institution, Diabetes Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

2 Internal Medicine Resident, Kerman Medical University, Kerman, Iran.

3 Department of Exercise Physiology, Shahid Bahonar University, kerman, Iran.

4 Musculoskeletal Rehabilitation, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.nces, Ahvaz, Iran.


Background and Objective: The aim of this study is determination of the prevalence of the cardiovascular risk factors between diabetic patients attending to Golestan hospital in Ahvaz.
Subjects and Methods: In this cross-sectional study 209 diabetic patients from Golestan hospital diabetic clinic in Ahvaz enrolled. A questionnaire completed after direct interview examination and laboratory assessment. The data were analyzed by SPSS 17 soft ware.
Results: Thetotal number of patients was 209 [144 female (68.9%) and 65 male (31.1%)] with mean age of 55.52 ±10.32 years old and mean of duration of disease 6.72±6.39   years. Overall, 57.6% of patients had arterial hypertension and 80.8% were in uncontrolled diabetes mellitus as glycosilated hemoglobin more than 7%. 49% of patients had cholesterol more than 200, 60.7% triglyceride more than 150, 52.8% LDL-C more than 100 and 59.8% low level of HDL-C(less than 40 mg/dl in male and 50 mg/dl in female). The prevalence of microalbominuria was 68.4%, macroalbominuria 5.8% and cigarette smoking 15.9%.
Conclusion: Cardiovascular risk factors are frequent among patients referred to hospital of Ahvaz spicily hypertension and diabetic nephropathy was more common.  Thus prevention policies are necessary for confront.


1-Adler AI, Neil HA, Manley SE, Holman RR, Turner RC. Hyperglycemia and hyperinsulinemia at diagnosis of diabetes and their association with subsequent cardiovascular disease in the United Kingdom prospective diabetes study (UKPDS 47). Am Heart J 1999;138(5Pt 1):S353-9.
2-International Diabetes Federation (IDF) Atlas. Availabe at: URL: http:// Accessed monyh day, year.
3-Fauci AS, Braunwald E, Kasper DL, Hauser SL, Longo DL. Harrison’s Principles of Internal Medicine. 18th ed.  New York: McGraw-Hill; 2011. P. 2290-1.
4-Nathan DM, Cleary PA, Backlund JY, Genuth SM, Lachin JM, Orchard TJ, et al. Intensive diabetes treatment and cardiovascular disease in patients with type 1 diabetes. N Engl J Med 2005;353(25):2643-53.
5-Khalangot M, Tronko M, Kravchenko V, Kulchinska J, Hu G. Body mass index and the risk of total and cardiovascular mortality among patients with type 2 diabetes: a large prospective study in Ukraine. Heart 2009;95(6):454-60.
6-Kalaitzidis R, Bakris G. Management of hypertension in patients with diabetes: the place of angiotensin-II receptor blockers. Diabetes Obes Metab 2009;11(8):757-69.
7-Yokoyama H, Oishi M, Kawai K, Sone H. Reduced GFR and microalbuminuria are independently associated with prevalent cardiovascular disease in Type 2 diabetes: JDDM study 16. Diabet Med 2008;25(12):1426-32.
8-Klausen KP, Parving HH, Scharling H, Jensen JS.  Microalbuminuria and obesity: impact on cardiovascular disease and mortality. Clin Endocrinol (Oxf) 2009;71(1):40-5.
9-Barnett E, Casper ML, Halverson JA, Elmes GA, Braham VE, Majeed ZA, et al. Men and Heart Disease: An Atlas of Racial and Ethnic Disparities in Mortality. Morgantown: Office for Social Environment and Health Research, West Virginia University; 2001.
10-Behavioral Risk Factor Surveillance System. Centers for Disease Control. Available at: URL: Accessed month day, year.
11-Matthews KA, Sowers MF, Derby CA, Stein E, Miracle-McMahill H, Crawford SL, et al. Ethnic differences in cardiovascular risk factor burden among middle-aged women: Study of Women's Health Across the Nation (SWAN). Am Heart J 2005;149(6):1066-73.
12-Arthur L, Klatsky, MD, Mary Anne Amnstrong, MA. Cardiovascular risk factors among Asian Americans living in northern california. Am J Public Health 1991;81(11):1423-8.
 13- Franz KB, Bailey SM .Geographical Variations in heart deaths and diabetes: effect of climate and a possible relationship to magnesium. J Am Coll Nutr 2004;23(5):521S–4.
14-Tosiello L. Hypomagnesemia and diabetes mellitus. A review of clinical implications. Arch Intern Med 1996;156(11):1143–8.
15-Rosolova H, Mayer O Jr, Reaven G. Effect of variations in plasma magnesium concentration on resistance to insulin-mediated glucose disposal in nondiabetic subjects. J Clin Endocrinol Metab 1997;82(11):3783–5.
16-Kao WH, Folsom AR, Nieto FJ, Mo JP, Watson RL, Brancati FL. Serum and dietary magnesium and the risk for type 2 diabetes mellitus: the Atherosclerosis Risk in Communities Study. Arch Intern Med 1999;159(18):2151–9.
17-Ford ES. Serum magnesium and ischaemic heart disease: findings from a national sample of US adults. Int J Epidemiol 1999;28(4):645-51.
18-Rasmussen HS, Aurup P, Hojberg S, Jensen EK, McNair P. Magnesium and acute myocardial infarction. Transient hypomagnesemia not induced by renal magnesium loss in patients with acute myocardial infarction. Arch Intern Med 1986;146(5):872–4.
19-Arlyn G, Aaron L. Many people with diabetes do not know or heed dangers of hot weather. 2010. Available at: URL: http:// Accessed month day, year.  
20-Semenza JC, McCullough JE, Flanders WD, McGeehin MA, Lumpkin JR. Excess hospital admissions during the July 1995 heat wave in Chicago. Am J Prev Med 1999;16(4):269–77.
21-Semenza JC. Acute renal failure during heat waves. Am J Prev Med 1999;17(1):97.
22-Bagshaw SM, Laupland KB, Doig CJ, Mortis G, Fick GH, Mucenski M, et al. Prognosis for long-term survival and renal recovery in critically ill patients with severe acute renal failure: a population-based study. Crit Care 2005;9(6):R700–9.
23-Lee DC, Folsom AR, Pankow JS, Brancati FL. Cardiovascular events in diabetic and nondiabetic adults with or without a history of myocardial infarction. Circulation 2004;109(7):855-60.
24-Safaei H, Amini M, Behrouz ZH, Teymouri A. [Cardiovascular risk factors in patients with newly diagnosed type 2 diabetes]. Iran J Endocrinol Metab 2006;29:31-8. [In Persian]
25-Bonackdaran SH, Taghavi M. Cardiovascular risk factors in patients with type 2 diabetes in Mashhad City. Iran J Endocrinol Metab 2010;12(1):1-6. [In Persian]
26-Al-Maskari F, El-Sadig M, Norman JN. The prevalence of macrovascular complications among diabetic patients in the United Arab Emirates. Cardiovasc Diabetol 2007;6:24.
27-Agarwal AK, Singla S, Singla S, Singla R, Lal A, Wardhan H, et al. Prevalence of coronary risk factors in type 2 diabetics without manifestations of overtcoronary heart disease. J Assoc Physicians India 2009;57:135-42.
28-Adler AI, Stratton IM, Neil HA, Yudkin JS, Matthews DR, Cull CA, et al. Association of systolic blood pressure with macrovascular and microvascular complications of type 2 diabetes (UKPDS 36): prospective observational study. BMJ 2000:321(7258);412-9.
29-Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL Jr, et al. The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report. JAMA 2003;289:2560-72.
30-Al-Amer RM, Khader Y, Malas S, Abu-Yghi N, Ajlouni K. Prevalence of risk factors of diabetic retinopathy among Jordanian patients with type 2 diabet. Digital journal of ophthalmology 2008;14(2):1-4.
31-Robles NR, Mena C, Velasco J, Angulo E, Garrote T, Garcia Gallego F. [Microalbuminuria-related cardiovascular risk in diabetic patients and hypertensive (non diabetic) population]. Med Clin (Barc) 2008;130(6):206-9. [In Spanish]
32-Aghamohamadzade N, Najafipur F, Asgarzadeh AA, Bahrami A, Niafar M, Mobassery M, et al. Prevalence of diabetic nephropathy in patient with type 2 diabetes. J Gorgan Univ 2009;11(1):62-6. [In Persian]
33-Jerums G, MacIsaac RJ. Treatment of microalbuminuria in patients with type 2 diabetes mellitus. Treat Endocrinol 2002;1(3):163-73.
 34-Bangstad HJ, Østerby R, Rudberg S, Hartmann A, Brabrand K, Hanssen KF. Kidney function and glomerulopathy over 8 years in young patients with Type I (insulin-dependent) diabetes mellitus and microalbuminuria. Diabetologia 2002;45(2):253-61.
35-Barnett E, Casper ML, Halverson JA, Elmes GA, Braham VE, Majeed ZA, et al. Men and Heart Disease: An Atlas of Racial and Ethnic Disparities in Mortality. Morgantown: Office for Social Environment and Health Research, West Virginia University; 2001.
36-lawlor DA, Smith GD, Mitchell R, Ebrahim S. Adult blood pressure and climate conditions in infancy: a test of the hypothesis that dehydration in infancy is associated with higher adult blood pressure. Am J Epidemiol 2006;163(7):608-14.
37-Pan CY, Ho LT, Soegondo S, Prodjosudjadi W, Suwanwalaikorn S, Lim SC, et al. Prevalence of albuminuria and cardiovascular risk profile in a referred cohort of patients with type 2 diabetes: an Asian perspective. Diabetes Technol Ther 2008;10(5):397-403.
38-Lubree HG, Rege SS, Bhat DS, Raut KN, Panchnadikar A, Joglekar CV, et al. Body fat and cardiovascular risk factors in Indian men in three geographical locations. Food Nutr Bull 2002;23(3 Suppl):146-9.
39-WHO Study Group. Prevention of Diabetes mellitus, WHO technical series 844. Geneva: World health organization; 1994.
40-Khan CR, Weir Gc, eds. Joslin’s diabetes mellitus. Philadelphia: Lea & Febiger; 1994.