Comparison between the growth indices among Low Birth and Normal Birth Weight Infants during the First 6 Months of Life in Ahvaz, 2009

Document Type : Original Article


1 Department of Neonatology, School of Medicine, Ahvaz Jundishapur University of Medical Science, Ahvaz, Iran.

2 Departmant of Pediatrics, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

3 Pediatrician, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.


Background and Objective:  To compare the trend of increase of growth indices among infants with low birth weight and infants with normal birth weight in the first 6 months of life.
Subjects and Methods: One hundred and thirty five low birth weight infants and 135 infants with normal birth weight were compared during a one-year study period 2009) and their demographic data included birth body weight, length and head circumference at birth, 2, 4 and 6 months of life, type of diet, birth number, sex, type of their mother's marriage and educational state were collected by a questionnaire trend of increase of growth indices among
Results: In first 6 months of life, in the LBW group the mean body weight was 5127±1076 g (p=0/001), mean body length was 17.8±3 cm (p=0.013) and mean head circumference was 9.1±1 cm (P<0.001), which was more than group with normal birth weight. In both groups, the average body weight, length and head circumference in males was higher than females. In the LBW group, the mean body weight in infants fed with breast milk was higher than infants fed with formula milk at age of 2 months.
Conclusion: This study showed that although mean increase of growth indices in infants with low birth weight is similar to average growth state in infants with normal birth weight, but still growth of this group at end of 6 months of age is less than group with normal birth weight.


1-Rondó PH, Tomkins AM. Chest circumference as an indicator of intrauterine growth retardation. Early Hum Dev 1996;44(3):161-7.
2-Khalil E, Ibrahim A, Zeiny NE-, Greiw A. Pattern of growth and development  of premature children at the age of two and three years in Alexandria , Egypt, parts 1 and 2. Eastern Mediterranean health J 1995;1(2):176-93.
3-Darendeliler F, Coban A, Bas F, Bundak R, Disci R, Sükür  M, et al. Catch-up growth in appropriate- or small-for-gestational age preterm infants. Turk J pediater 2008;50(3):207-13.
4-Knops NBB, Sneeuw KCA, Brand R, Hille ETM, den Ouden AL, Wit JM, et al. Catch-up growth up to ten years of age in children born very preterm or with very low birth weight. BMC Pediatr 2005;26(2):204-8.
5-Oliveira MG, Silveira RC, Procianoy RS. Growth of very low birth weight infants at 12 months corrected age in southern Brazil. J Trop Pediatr. 2008;54(1):36-42.
6-Lin CM, Chen CW, Chen PT, Lu TH, Li CY. Risks and causes of mortality among low-birthweight infants in childhood and adolescence. Paediatr Perinat Epidemiol 2007;21(5):465-72.
7-Oliveira ZA, Bettiol H, Gutierrez MR, Silva AA, Barbieri MA. Factors associated with infant and adolescent mortality. Braz J Med Biol Res 2007;40(9):1245-55.
8-Xu B, Rantakallio P, Järvelin MR. Mortality and hospitalizations of 24-year-old members of the low-birthweight Cohort in northern Finland. Epidemiology 1998;9(6):662-5.
9-Hack M, Schluchter M, Cartar L, Rahman M, Cuttler L, Borawski E. Growth of very low birth weight infants to age 20 years. Pediatrics 2003;112(1 Pt 1):e30-8.
10-Luo ZC, Albertsson-Wikland K, Karlberg J. Length and body mass index at birth and target height influences on patterns of postnatal growth in children born small for gestational age. Pediatrics 1998;102(6):E72.
11-Downes B, Downes R, Foord F, Weaver L. Outcome of low birth weight infants in a West African village. J Trop Pediatr 1991;37(3):106-10.
12-Bakketeig LS, Jacobsen G, Skjaerven R, Carneiro IG, Knudsen LB. Low birthweight and mortality: the tendency to repeat low birthweight and its association with early neonatal and infant mortality. Paediatr Perinatal Epidemiol 2006;20(6):507-11.
13-Andersen AM, Osler M. Birth dimensions, parental mortality, and mortality in early adult age: a cohort study of  Danish men born in 1953. Int J Epidemiol 2004;33(1):92-9.
14-Abyazdan Z, Ehsanpoor S, Javanmardi Z. A comparative study on growth pattern of low birth weight and normal birth weight neonate. Iran J Nursing  Midwifery Res 2007;12(3):106-10.
15-Dodrill P, Cleghorn G, Donovan T, Davies P. Growth patterns in preterm infants born appropriate for gestational age. J Paediatr Child Health 2008;44(6):332-7.
16-Li HR, Feng LY, Zheng MS. [A Longitudinal study of growth and development of  low birth weight infants]. Zhonghua Hu Li Za Zhi 1996;31(2):63-7. [In Chinese]
17-Kirsch S, Weiss B, Schon K, Rappold GA. The definition of the Y chromosome growth-control gene (GCY) critical region: relevance of terminal and interstitial deletions. J Pediatr Endocrinol Metab 2002;15 Suppl 5:1295-300.
18-Casey PH, Kraemer HC, Bernbaum J, Yogman MW, Sells J. Growth status and growth rates of a varied sample of low birth weight, preterm infants: a longitudinal cohort from birth to three years of age. J pediatr 1991;119(4):599-605.
19-Shulman RJ, Schanler RJ, Lau C, Heitkemper M, Ou CN, Smith EO. Early feeding, feeding tolerance and Lactase activity in preterm infant. J Pediatr 1998;133(5):645-9.
20-Cavell B. Gastric emptying in infants fed human milk or infant formula. Acta Paediatr Scand 1981;70(5):639-41.
21-Nayeri F, Kheradpisheh N, Shariat M, Akbari Asbagh P. [A comparison between the growth trend of normal and low birth weight newborns during the first year of life]. Tehran Univ Med J 2009;67(4):296-302. [In Persian]