Blood Selenium Level in Hemodialysis Patients in Shahrekord

Document Type : Original Article


1 Department of nutrition and biochemistry, faculty of Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran

2 Department of Clinical Biochemistry Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran

3 Faculty of Veterinary Medicine, Shahrekord University, Shahrekord, Iran


Introduction: Selenium (Se) is a potent antioxidant and therefore can prevent unwanted and harmful reactions that occur in the body due to the accumulation of free radicals and toxins. Se deficiency can be a result of an inappropriate diet or illness. Hemodialysis is considered as the dominant treatment in the end stage of renal failure. The level of some trace elements in the blood of these patients increases and some others are reduced. The aim of this study was to determine the blood Se level in these patients.
Materials and Methods: 123 hemodialysis patients were evaluated. Se content in whole blood was measured by atomic absorption spectrophotometric method with graffiti furnace after digestion.
Results: In this study, 123 cases of dialysis patients were 67 men (54.47%) and 56 women (45.56%). The amount of Se in the blood of hemodialysis patients was 52.24 ± 12.66 μg /L. Se levels in male and female were 52 ± 13.04 and 53 ± 12.77 μg /L respectively, which were not statistically significant. The present study also showed that dialysis duration did not have a significant effect on Se blood levels.
Conclusion: The results of this study showed that the blood level of Se in hemodialysis patients is less than normal, and there is no significant difference between the two sexes regarding the content of Se blood.
Keywords: Selenium. hemodialysis. oxidative stress


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