Myoepithelioma of a Minor Salivary Gland of the Palate: Case Report

Document Type : Case Report


1 Department of, Periodontology. Dental School, jundishapour University of Medical Sciences, Ahvaz, Iran.

2 Department of Oral & Maxillofacial Pathology, Dental School, International Branch, Shahid Beheshti University of

3 Department of Oral & Maxillofacial Pathology, Dental School, Shahid Beheshti University of Medical Sciences, Tehran, Iran

4 Dental School, University of Medical Sciences, Ahvaz, Iran.


Myoepithelioma is a rare neoplasm of salivary glands, generally occurring in the parotid and less often in the minor salivary gland of the oral cavity. Vimentin and S100 protein are very sensitive but nonspecific immunohistochemical markers of neoplastic myoepithelium. This report is a rare case of myoepithelioma of the palate of a 25-year-old woman who suffered the disease for two years. The numerous phenotypic expressions of the myoepithelial cell, associated with the rarity of this tumor, may challenge the pathologist.
Sci Med J 2012; 10(6):693-698


1-Ferri E, Pavon I, Armato E, Cavaleri S, Capuzzo P, Ianniello F. Myoepithelioma of a minor salivary gland of the cheek: Case report. Acta Otorhinolaryngol Ital. 2006; 26: 43-6.
2-Perez DE, Lopes MA, De Almeida OP, Jorge J, Kowalski LP. Plasmacytoid myoepithelioma of the palate in a child. Int J Paediatr Dent. 2007; 17: 223-7.
3-Nakaya K, Oshima T, Watanabe M, Hidaka H, Kikuchi T, Higashi K, et al. A case of myoepithelioma of the nasal cavity. Auris Nasus Larynx. 2010; 37: 640-3.
4-Da Silveira EJ, Pereira AL, Fontora MC, De Souza LB, De Almeida Freitas R. Myoepithelioma of minor salivary gland--an immunohistochemical analysis of four cases. Braz J Otorhinolaryngol. 2006; 72: 528-32.
5-Astarci HM, Celik A, Sungu N, Ustun H. Cystic clear cell myoepithelioma of the parotid gland. A case report. Oral Maxillofac Surg. 2009; 13: 45-8.
6-Cuesta Gil M, Bucci T, Navarro Cuellar C, Duarte Ruiz B, Pannone G, Bufo P, et al. Intraosseous myoepithelioma of the maxilla: Clinicopathologic features and therapeutic considerations. J Oral Maxillofac Surg. 2008; 66: 800-3.
7-Bernaba BN, Binder SW, Cassarino DS. Myoepithelioma with melanocytic colonization (melanocytic myoepithelioma): A case report. J Cutan Pathol. 2009; 36: 697-701.
8-Ghosh A, Saha S, Saha VP, Sadhu A, Chattopadhyay S. Infratemporal fossa myoepithelial carcinoma-a rare case report. Oral Maxillofac Surg. 2009; 1359-62.
9-Vékony H, Röser K, Löning T, Raaphorst FM, Leemans CR, Van der Waal I, et al. Deregulated expression of p16INK4a and p53 pathway members in benign and malignant myoepithelial tumours of the salivary glands. Histopathology. 2008; 53: 658-66.
10-Wang S, Shi H, Wang L, Yu Q. Myoepithelioma of the parotid gland: CT imaging findings. AJNR Am J Neuroradiol. 2008; 29: 1372-5.
11-Acikalin MF, Pasaoglu O, Cakli H, Gürbüz K, Canaz F. Malignant myoepithelioma of the palate: a case report with review of the clinicopathological characteristics.Yonsei Med J 2009 31;50:848-51.