Effect of a 5-Day Vitamin C Supplements on Immunological Stress Caused by an Aerobic Exercise Session in Young Women

Document Type : Original Article


1 MSc Student in Exercise Physiology.Islamic Azad University, Science and Research Bushehr, Bushehr, Iran.

2 PhD in Exercise Physiology.Department of Exercise Physiology, Islamic Azad University, Science and Research Department of Physical Education in Bushehr, Bushehr, Iran.

3 PhD in Exercise Physiology. Department of Exercise Physiology, Islamic Azad University, Science and Research Department of Physical Education in Bushehr, Bushehr, Iran.


Background and Objective: Physical activity and some antioxidants, such as vitamin C, can affect the immune system. This The current research attempts to determine the immune system reaction following consumption of vitamin C after an aerobic physical activity.
Subjects and Methods: In the present experimental work, 24 females aged 32 y were selected by random sampling and divided into two 12-subjects groups, first group (vitamin C) and the second group (placebo). In the pre-test, the serum baseline measurements for IgG and IgA were made for both groups. Then, 500 mg of vitamin C was given to the experimental group once daily for 5 days. After five days, blood samples were taken from both groups. Finally, on the 6th day immediately blood sampling was performed after aerobic physical exercise (Bruce test). And then was taken to the lab by immunological examination after analyzing the data, the required information was collected.
Results: The results showed that after aerobic activity level of IgG and IgA were significantly higher (P <0.05), while plasma cortisol levels were significantly lower (P <0.05) in the vitamin C group compared to the placebo group.
Conclusion: The consumption of vitamin C following aerobic exercise has an effect on the levels of A and G immunoglobulin’s and serum cortisol levels, and the repressive effects of the exercise-induced immune system are somewhat reduced.


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