Improved Method for the Translational Technique to Treatment of Whole Skin in Cancer Patients

Document Type : Original Article

Authors

1 Department of Medical Physics, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

2 Department of Radiotherapy and Oncology, Golestan Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Abstract

Background and Objectives: There are several techniques for the treatment of whole skins in the standing position of patient, in spite of some patients can not able to stand. In addition, most of these techniques require a large treatment rooms, but there is no problem in translational technique. In this study we try to design transfer technique for treating skin on the linear accelerator in Ahvaz Golestan hospital.
Subjects and Methods: Measurements were made at radiation oncology department of Ahvaz Golestan hospital by Varian linear accelerator with 10×10 cm2 applicator, using a parallel plate dosimeter and water phantom with dimensions 20 × 30 × 30 cm3 at 4 and 6 Mev energies. Water phantom moves in front of electron sources to get a steady dose by all points at Zref depth. We could obtain a couch rate of displacement under the applicator.
Result: Dosimetry results showed that if the couch moves symmetricallyas mach as equal to twice the length of the applicator plus the length of the phantom, all the points at any depth will get nearly a uniform dose.
Conclusion: The results revealed that the technique a good one to deliver a uniform dose to all points of the phantom at Zref.
 

Keywords

References

1-Anacak Y, Arican Z, Bar-Deroma R, Tamir A, Kuten A. Total skin electron irradiation: Evaluation of dose uniformity throughout the skin surface. Medical Dosimetry 2003;28:31-34.
2-Andreo P, Brahme A. Mean energy in electron beams. Med Phys 1981; 8: 682-687.
3-Andrews JR, Swain RW. The radiation therapy of human cancer with accelerated atomic particles. Med Ann Dist of Columbia 1957; 26: 13-16.
4-Diamantopoulos S, Platoni K, Dilvoi M, Nazos I, Geropantas K, Maravelis G, "et al". Clinical implementation of total skin electron beam(TSEB)therapy: A review of the relevant literature. Physica Med 2011; 27: 62-68.
5-Bourgeouis JP, Bridier A, Bouhnik H, Schlienger M. Whole cutaneous irradiation in mycosis fungoides with 55 kV x-rays. Bull of cancer 1977; 64: 313-322.
6-Szur L, Silvester J, Bewley DK.Treatment of the whole body surface with electron. Lancet 1962; 1: 1373-1377.
7-Trump JG, Wright KA, Evans WW, Anson JH, Hare HF, Fromer JL, "et al". High energy electrons for the treatment of extensive superficial malignant lesions. Roentgenol 1953; 69: 623-629.
8-Blasko J, Becker L, Griffin TW, Tong DYK, Groundine M. Electron beam therapy of mycosis fungoides. Acta Radial Oncol 1979; 18: 321-325.
9-Bunn PA, Hoffman SJ, Norris D, Golitz LE, Aeling JL. Systemic therapy of cutaneous T-cell lymphomas(mycosis fungoides and Sezary syndrome). Ann Intern Med 1994; 121: 592-602.
10-Wu JM, Leung SW, Wang CJ, Chui CS. Lying-on position of total skin electron therapy. Int J.Radiat Oncol Biol Phys 1997; 39: 21-528.
11-Becker M, Hoppe RT, Knox SJ. Multiple courses of high-dose total skin electron beam therapy in the management of mycosis fungoides. Int J Radiat Oncol Biol Phys 1995; 32: 1445-1449.
12-Gerbi BJ, Khan FM, Deibel FC, Kim TH. Total skin electron arc irradiation using a reclined patient position. Radiation Oncology Biol 1989;17: 397-404.
13-Van Der Merwe DG. Total skin electron therapy: A technique which can be implemented on a conventional electron linear accelerator. Radiation Oncology Biol 1993; 27: 391-396.
14-Ulutin HC, Beyan c, Pak Y. Total skin electron beam therapy for cutaneous T-cell lymphoma: Turkish experience with translational technique. Hematologia 2002; 32: 397-403.
15-Anacak Y,  Arican Z,  Drumea K, Rosenblatt E, Tamir A, Chetver L, "et al". Total skin electron irradiation in mycosis fungoides:Comparison between a modified Christie hospital translational technique and the Stanford technique. Leukemia and Lymphoma 2002; 43(11): 2093-2097.
16-Freeman CR, Suissa S, Shenouda G, Vuong T, Souhami L, Pla M, "et al". Clinical experience with a single field rotational total skin electron irradiation technique for cutaneous T-cell lymphoma. Radiation and Oncology 1992;  24: 155-162.
17-Shouman T, El-Taher Z. Total skin electron therapy: A modified technique for small room linear accelerator. J of the Egyptian Nat 2004; 16: 202-209.
18-Platoni K, Diamantopoulos S, Panayiotakis G, Kouloulias V, Pantelakos P, Kelekis N,"et al". First application of total skin electron beam irradiation in Greece: setup,measurements and dosimetry. PhysicaMedica 2012; 28: 174-182.
19-Williams PC, Hunter RD, Jackson SM. Whole body electron therapy in mycosis fungoides-a successful translational technique achieved by modification of an established linear accelerator. British Journal of Radiology 1979; 52: 302-307.
20-Khan FM. The physics of radiation therapy. 4th ed. Philadelphia: Lippincott Williams & Wilkins; 2010. P. 299-301.
21-Karzmark CJ, Lovinger R, Steele RE. A technique for larg-field, superficial electron therapy. Radiology. 1960; 74: 633-643.
22-Page V, Gardner A, Karzmark CJ. Patient dosimetry in the electron treatment of large superficial lesions. Radiology 1970;  94: 635-641.
23-Van Der Merwe DG. Total skin electron therapy: A technique which can be implemented on a conventional electron linear accelerator. Radiation Oncology Biol 1993; 27: 391-396.
24-Shouman T, El-Taher Z. Total skin electron therapy: A modified technique for small room linear accelerator. J of the Egyptian Nat 2004; 16: 202-209.
25-Freeman CR, Suissa S, Shenouda G, Vuong T, Souhami L, Pla M, "et al". Clinical experience with a single field rotational total skin electron irradiation technique for cutaneous T-cell lymphoma. Radiation and Oncology 1992; 24: 155-162.
26-Reynard EP, Evans MD, Devic S, Parker W, Freeman CR, Roberge D, "et al". Rotational total skin electron irradiation with a linear accelerator. J Appl Clin Med Phys 2008; 9(4): 2793.
27-Williams PC, Hunter RD, Jackson SM. Whole body electron therapy in mycosis fungoides-a successful translational technique achieved by modification of an established linear accelerator. British Journal of Radiology 1979; 52: 302-307.
28-Rosenblatt E, Kuten A, Leviov M, Cederbaum M. Total skin electron irradiation in mycosis fungoides dose and fractionation considerations. Leuk Lymphoma 1998; 30(1-2): 143-51.
 
Jundishapur Scientific Medical Journal
Volume 13, Issue 5 - Serial Number 92
November and December 2017
Pages 573-580

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History

  • Receive Date: 10 March 2014
  • Revise Date: 14 March 2015
  • Accept Date: 03 August 2014

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