Evaluation of Frequency Growth Disorder in 6 to 60 Months Old Children with Congenital Heart Disease in Ahvaz from 2011 to 2013

Document Type : Original Article


1 Associate Professor of Children.Department of Children, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Ahvaz, Iran.

2 Assistant Professor of Children.Department of Pediatrics, Ahvaz Jundi-Shapur University of Medical Sciences, Ahvaz, Iran. Medical Student, Jundishapur University of Ahvaz, Ahvaz, Iran.

3 Assistant Professor of Children's Department. 1,3,4-Department of Children, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Ahvaz, Iran.

4 Assistant Professor of Children.Department of Children, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Ahvaz, Iran.

5 Medical Student. Medical Student, Ahvaz Jundi-Shapur University of Medical Sciences, Ahvaz, Iran.


Background and Objective: Congenital heart disease (CHD) is one of the reasons of growth disorder and mortality in children all over the world. Growth disorder in these children affects their prognosis and mortality before and after cardiac surgery. In this study, we evaluated growth factors in children affected with CHD to assess their condition for appropriate intervention.
Subjects and Methods: Growth parameters including weight, height, head circumference and body mass index records of 368 admitted children aged 6 to 60 months old with CHD in Ahvaz Golestan hospital from 2011 to 2013 were analyzed in this descriptive-epidemiologic study. Collected data were analyzed by using SPSS software and Chi Square, Fisher and Logistic regression.
Results: Underweighting was the most common type of growth disorders (49.2%) especially in 12-23 month age group. Ventricular septal defect (VSD) was the most common cardiac lesion, and growth disorder was seen in VSD and TGA more than other cardiac disorders. Growth failure was more common in cyanotic CHD, and the most severe disorders were related to cyanotic patients with pulmonary hypertension, which was statistically significant (P<0.05).
Conclusion: According to the results, cyanosis and pulmonary hypertension were detected as two important factors for growth failure in children with CHD, and sex of patients was irrelevant. Thus, timely diagnosis and management of growth disorder in these children can improve their growth retardation and prognosis after corrective and palliative surgery.


1-Shadzi Sh. The National Programs for Natal Surveillance. Text Book of Public Health. 1st ed. Tehran: Arjmand; 2004. P. 184.
2-Kliegman RM, Das UG. Intrauterine growth retardation. In: Fanaroff AA, Martin RJ, editors. Neonatal-perinatal medicine: Diseases of the fetus and infant. 7th ed. Philadelphia; Mosby: 2001. P.246.
3-Kliegman RM, Stanton BF, Schor NF: Nelson Textbook of Pediatrics. 20th ed, Volume1. 2016. pp: 50-89, Volume2. 2016. pp: 2182-2230.
4-Vieria TC, Trigo M, Alonso RR, Riberio RH, Cardoso MR. Assessment of food intake in infants between 0 and 24 months with congenital heart disease. Arq Bras Cardiol 2007; 89(4): p 219-224.
5-Varan B, Tokel K, Yilmaz G. Malnutrition and growth failure in cyanotic and acyanotic congenital heart disease with and without pulmonary hypertension. Arch Dis Child. 1999 Jul; 81(1): 49-52.
6-Kao YI, Wang R, Hwang B. Life adjustment of school age children with congenital heart disease after corrective surgery. Journal of Nursing 2000; 47: 43-45.
7-Allen HD, Driscoll DJ, Shaddy RD, Feltes TF. Moss and Adams' Heart Disease in Infants, Children and Adolescents: Including the Fetus and Young Adult. 7th ed. Philadelphia: Lippincott Williams & Wilkins, 2008: pp: 524-541.
8-Martorell R, Haschke F: Nutrition and Growth. Philadelphia: Lippincott Williams & Wilkins, 2001: pp: 22-47.
9-Emami Moghadam AR. Failure to thrive and its patterns in children with heart disease in Ahwaz 2007. Medical Science Journal 2009; 8(3): pp: 361-368.
10-Noori N. Growth status in children with congenital heart disease. Medical Science Journal of Tabriz University (In Persian) 2010: pp: 78-83.
11-Boctor D, Pillo-Bloka F. Nutrition after cardiac surgery for infants with congenital heart disease. Nutrition in Clinical Practice 1999; 14:111-115.
12-Chung Y, Chi-Wen C. Growth and development of children with congenital heart disease. Journal of advanced nursing 2004; 47(3): pp: 260-269.
13-Nasiruzzaman AH, Hussain MZ, Baki MA, Tayeb MA, Mollah MN. Growth and developmental status of children with congenital heart disease. Bangladesh Medical Journal. 2011; 40(2): 54-7.
14-Samadi M, Siamak SH, Mohammadpour Shateri M, Habibzadeh A. Growth Parameters and Insulin Like Growth Factor-1: Comparison between Cyanotic and Acyanotic Congenital Heart Disease and Normal Children. Life Science Journal 2013; 10(4). pp: 577-580.
15-Hassan BA, Albanna EA, Morsy SM, Siam AG, et al. Nutritional status in children with un-operated congenital heart disease: an Egyptian center experience. Frontiers in Pediatrics Journal 2015; volume3. pp: 1-5.
16-Thompson G, Reyes T, Rabiele B. The nutritional status of the child with congenital cardiopathy. Arc Inst Cardiol Mex 1998; 68(2): p 119-230.
17-Villasis-Keever MA, et al. Frequency and risk factors associated with malnutrition among children with congenital heart disease in a cardiology hospital. Salud Publica Mex 2001; 43(4): pp: 313-323.
18-Blasquez A, et al. Evaluation of Nutritional ststus and support in children with congenital heart disease. European Journal of Clinical Nutrition 2016; 70 pp: 528-531.
19-Ratanachu-Ek S, Ponqdara A. Nutritional status of pediatric patients with congenital heart disease: pre-and post-cardiac surgery. J med assoc Thai 2011; 94(3): pp: 133-137.