Skeletal Changes in Patients with Beta –Thalassemia Major in Ahvaz

Document Type : Original Article

Authors

1 Assistant professor, School of Dentistry, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

2 Assistant Proffessor of Pedodontics.Department of Pedodontics, School of Dentistry, Ahvaz, Jundishapur University of Medical Sciences, Ahvaz, Iran.

3 Dentist.School of Dentistry, Ahvaz, Jundishapur University of Medical Sciences, Ahvaz, Iran.

Abstract

Background and Objective: Thalassemia major has severe clinical symptoms with craniofacial defects that produce esthetic problems in patients. Orthodontic treatment and surgical reconstruction in these patients have had good esthetic results and therefore satisfying pschycosocial effects. Researches have shown an increase in the level of life quality corresponding to health improvement in thalassemic patients. More knowledge and information is necessary for better treatment of skeletal problems in thalassemia.
Subjects and Methods: This descriptive and analytic study was performed on 48-beta thalassemia major patient and 48 normal samples. They were divided into two groups (24 persons) based on their genders. Including criteria for samples were : being more than 15 years  old, not being affected by special disorders, not having orthodontic and orthopedic treatment, having Cl I profile, normal facial height, Cl I molar relationship, normal overbite and over jet and the presence of all permanent teeth (except third molar). Cephalometric analysis was used for evaluation of cephalograms. The results were analyzed using descriptive statistical and paired sample T-test (P<0.005).
Results: SNA angle did no significant increase, but SNB and ANB angles significantly decreased (P<0.005).
The angle between SN-Occlusal plans, Frankfort - y-axis plans and basal plans showed increase, but the angle between Frankfort - facial plans (P<0.005) and the distance between pog-NB plan showed decrease (P<0.005).
Conclusion: Beta thalassemia major induces Cl II malocclusion and long face growth pattern due to decrease in mandibular growth and decrease in posterior facial height.

Keywords

References

 
1-Pakshir H, Mina KH. Cephalometric analysis in patients with beta-thalassemia. Shiraz J Dent 2003;122:55-66.
2-Habibzadeh F, Yadollahie M, Merat A, Haghshenas M. Thalassemia in Iran; an over view. Arch Iran Med 1998;1:49-54.
3-Noori- Daloii MR, Moazami N, Farhangi S, Atalay A, Geren IN, Akar L, et al. Beta–thalassemia in Iran: a high incidence of nonsence codon 39 mutation on the island of Queshm. Hemoglobin 1994;18(6):449-53.
4-Bassimitci S, Yücel-Eroğlu E, Akalar M. Effects of thalassaemia major on components of the craniofacial complex. Br J Orthod 1996:23(2):157-62.
5-Scutellari PN, Orzincolo C, Andraghetti D, Gamberini MR. Cephalometric Analysis in beta-halassemia. Radiol Med(Torino) 1994; 87(4): 389-96.
6-Abu Alhaija ES, Hattab FN, al-Omari MA. Cephalometic measurements and facial deformities in subjects with beta-thalassaemia major. Eur J Orthod 2002;24(1):9-19 .
7-Amini F, Jafari A, Eslamian L, Sharifzadeh S. A cephalometric study on craniofacial morphology of Iranian children with beta-thalassemia major. Orthod Craniofac Res 2007;10(1):36-44.
Jundishapur Scientific Medical Journal
Volume 11, Issue 3 - Serial Number 78
July and August 2017
Pages 295-302

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History

  • Receive Date: 28 April 2010
  • Revise Date: 07 January 2012
  • Accept Date: 21 January 2012

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