The Evaluation of Dialysis Adequacy by KT/V in Hemodialysis Patients

Document Type : Original Article

Authors

1 Associate Professor of Nephrology.Department of Internal Medicine, Faculty of Medicine, Jundishapur University of Medical Sciences, Ahvaz, Iran.

2 General Practiotioner.Centre Responsible for Specific Patients in Khuzestan Province, Iran.

3 Assistant Professor of Nephrology.Department of Internal Medicine, Faculty of Medicine, Khorasan University of Medical Sciences,Mashhad, Iran.

Abstract

Background and Objective: Patients with ESRD need adequate dialysis. According to DOQI guidelines, minimum dialysis dose by KT/V in patients under hemodialysis (HD) is 1.2 or greater.
Subjects and Methods: In a cross- sectional study, we evaluated the value of KT/V among HD patients in shahid Beheshti Hospital of Abadan, Iran. HD was performed for 3 to 4 hours, using synthetic dialyzer and the bicarbonate- based dialysate. Blood flow rate, dialysate flow rate and ultrafiltration rate were 250 to 300 cc /min, 500cc/min and zero or 1 to 3 liters, respectively. Blood sampling for BUN was done immediately before and after the dialysis session.
We used the following equation to estimate the KT/V from the percent reduction in urea (PRU). KT/V = (0.026 ×PRU) – 0.460
Results: 54 HD patients (28 females and 26 males) with the mean age of 39 ± 14.2 years were enrolled in the study. The most common cause of ESRD was hypertension (24.07%) followed by, unknown (22.22%), DM (18.51%), Chronic Glomerulonephritis (14.81%), urinary tract abstraction (12.96%) and poly cystic kidney disease (7.40%).  KT/V was less than 1.2 in 87.03 patients (n=47). There was no significant difference in the valve of KT/V in men and women (P= 0.54) and in different hemoglobin concentration (p=0.58).
Conclusion: The results of the study show that the most of our HD patients have not received minimum dialysis dose and we should evaluate and correct its causes.

Keywords

References

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Jundishapur Scientific Medical Journal
Volume 11, Issue 1 - Serial Number 76
July and August 2002
Pages 43-48

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History

  • Receive Date: 11 October 2010
  • Revise Date: 20 December 2011
  • Accept Date: 03 January 2012

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