The Effect of Entonox Gas Inhalation on the Duration of Active Phase of Labor and Outcome of Delivery

Document Type : Original Article

Authors

1 Department of Obstetrics & Gynecology, Fertility Infertility and Perinatology Research Center, Ahvaz Jundishapur University of Medical Sciences. Ahvaz. Iran

2 Department of Obstetrics & Gynecology,Tamin Ejtemaee Hospital of Borujerd, Borujerd, Iran.

Abstract

Background and Objective: Annually, thousands of the elective caesarean sections are performed that the fear of labor pain is considered as the major underlying cause. Various methods are introduced for pain relief during labor. Prolongation of labor is one of the complications of some painless labor methods. The aim of this study was to investigate the effect of Entonox inhalation as a type of labor analgesia, on the duration of the active phase of labor and outcome of delivery.
Subjects and Methods: This is a clinical trial study which was performed on 200 pregnant women at the maternity ward of Ahvaz Emam Khomeini hospital. The women were randomly divided into two equal case and control groups (n= 100). The case group inhaled Entonox with a mask from the start of the active phase of labor, and the delivery was performed for the control group without Entonox use.
Result: The duration of active phase of labor in the case group was significantly shorter than the control group (4.07±2.1 hours in study group in comparison with 5.12±2.06 hours in control group). Furthermore us          e of Entonox not only caused decrease in the labor pain and increases in mothers' satisfaction, but also did not influence on the APGAR of the neonates.
Conclusions: The finding of this study demonstrated that Entonox gas is an effective and a safe method for relief of labor pain. In addition not only it reduces duration of active phase of labor, but also increases mothers' satisfaction.

Keywords


 
1-Cunningham FG, Donald C. Williams obstetrics. 23nd ed. USA: Appleton and Langce; 2009.
2-Dayan J, Creveuil C, Herlicoviez M. Role of anxiety and depression in the onset of spontaneous preterm labor. Am J Epidemiol 2002; 155(4): 293-301.
3-Hobel C, Culhance J. Role of psychosocial and nutritional stress on poor pregnancy outcome. J Nutr 2003; 133(5): 709-17.
4-Hamzegardeshi Z, Nemati N, Kashiri A. Painless delivery. Shahrod Proceedings of the Fifth National Congress of Medical Sciences. Shahrod: young researchers club; 2006. [Persian]
5-Johnson RC, Salade P. Obstetric complications and anxiety during pregnancy: Is there a relationship?. J Psychosom Dbstet Gyn 2003; 24: 1-14.
6-Miller RD. Textbook of Anesthesia. Philadelphia: Churchill livingstone Co; 2000. P 2024.
7-Wee M. Analgesia in labour: inhalational and parenteval anaesthesia & intensive care medicine 2003; 5(7): 233-4.
8-Rosen MA. Nitrous oxide for relief of labor pain: a systematic review. Am J Obstet Gynecol 2002; 186: S110-260.
9-Noroozi Nia Sh, Noroozi Nia H, Mahoori AR, Jamshidi K, Kakay Afshar M, Tahoori R. The effects of continuous in halation of entonox on labor pain relief. J Iranian Sol Anaesth Intensive Care 2005; 27(51): 57-62.
10-Aram S, Atari M. Comparison of labor pain with or without inhalation entonox. J Esfahan University Med Sci 1998; 16(53): 27-32.
11-Ji X, Qi H, Liu A. Clinical study on labor pain relief using the combined spinal-epidural analgesia and inhaling nitrous oxide. Zhonghua Fu Chan Ke Za Zhi 2002; 37(7): 398-401.
12-Chia YT, Arulkumaran S, Chua S, Ratnam SS. Effectiveness of transcutaneons electric nerve stimulator for pain relief in labor. Asia Oceania J Obs Gyn 1990; 16(2): 145-51.
13-Su F, Wei X, Chen X, Hu Z, Xu H. Clinical study on efficacy and safety of labor analgesia with in halation of nitrous oxide in oxygen. Zhonghua Fu Chan Ke Za Zhi 2002; 37(10): 584-7.
14-Carstoniu J , Levytam S, Norman P, Daley D, Katz Y, Sandler An. Nitrous Oxide in early labor. Safety and analgesic efficacy assessed by a double- blind, placebo- controlled study. Anesthesiology 1994; 80(1): 30-5.
15-Noroozi Nia Sh, Noroozi Nia H, Mahoori AR, Jamshidi K, Kakay Afshar M, Tahoori R. Effects of constant entonox inhale on pain lessness of delieveries. Jour of Anesthesiology and Intensive Care 2005; 51(2): 54-62.
16-Jahani soohrab N, Mirzakhani K, Hassanzadeh M. Effect of entonox on labor pain in women referred to Torbat Heidarieh maternity ward in 2004. Jour of Sabzawar University of Med Sciences 2004; 12(1): 27-31.
17-Yazdi Moghaddam H, Rahnamai Rahsepar F, Heydari A. Studying the effect of entonox gas on the APGAR of the neonates. Rafsenjan University Med. Sci 2011; 10(3) :165-174.
18-Dunen I , Rooks J. Use of nitrous oxide in midwifery practice – complementary, synergistic, and needed in the united states. Journal of Midwifery & Women's Health 2007; 52(3): 186-9.