Antibiotic Susceptibility Pattern of Staphylococcus aureus Isolated from Clinical Specimens Taken from Hospitalized Patients in Educational Hospitals of Ahvaz City, against Methicillin, Vancomycin, Linezolid and Macrolides in 2013

Document Type : Original Article

Authors

1 Department of Medical Microbiology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

2 Msc of General Microbiology

Abstract

Background and Objective: Staphylococcus aureus is one of the most important human pathogenic bacteria, which due to its becoming increasingly resistant to various antibiotics including penicillin, oxacillin, vancomycin, macrolides, linezolids required particular attention. The aim of this study was to evaluate the pattern rate of resistance of isolates collected from clinical samples among hospitalized patients in Golestan and Imam Khomeini hospitals in Ahwaz, Iran.
Subjects and Methods: In the present study, a total of 325 suspected isolates of Staphylococcus aureus collected from clinical samples, 200 isolates were identified as Staphylococcus aureus, after performance of standard diagnostic tests including mannitol salt agar, coagulase, DNase agar and catalase. The identified isolates were studied according to CLSI Standards by disc fusion method using antibiogram discs containing oxacillin, vancomycin, erythromycin, azithromycin or linezolid.    
Results: All isolates were sensitive to linezolid and vancomycin. Resistance against meticillin, azithromycin and erythromycin was 50, 61.5 and 59 %, respectively. In addition, 25% of islotaes of Staphylococcus aureus were concurrently resistant to meticillin, azithromycin and erythromycin.
Conclusion: Resistance to the methicillin relative to the previous years has increased noticeable, but there was no resistance to vancomycin and linezolid.
 

Keywords

References

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Jundishapur Scientific Medical Journal
Volume 13, Issue 4 - Serial Number 91
July and August 2014
Pages 465-474

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History

  • Receive Date: 08 April 2014
  • Revise Date: 25 May 2014
  • Accept Date: 09 June 2014

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