Comparing Endometrial Cancer in Women Younger and Older than 40 Years Referred to Radiotherapy-Oncology Department of Ahwaz Golestan Hospital from 2001-2012

Document Type : Original Article

Authors

1 Department The Head of Radiotherapy and Oncology, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

2 Intern of Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Abstract

Background and Objective: Endometrial cancer is the most common gynecologic malignancy in Europe and fourth common cancer in United State. The aim of this study was to gain insight about the statue of endometrial cancer in Khuzestan province over eleven year age.
Subjects and Methods: This  descriptive and  retrospective study included 130 medial records from patients with endometrial cancer referred to our Radiology-Oncology deparmtent of Golestan hopsital during eleven years (2001-2012). The patients were divided into two groups: 40 years age or youngr (group A) and older than 40 years (group B). The collected data were analyzed with SPSS 21 using descriptive  fisher exact test statistics.
Results: The file data showed that 10 % (13/130) of the patients  withendometrial cancerwere aged 40 or lower.84 % of  all patients had “endometrioid  type”. The prevalence of high-risk histology endometrial cancer (papillary serous and clear cell ) significantly were higher in group B (P=0.04). However poor histologic grade (grade 3) and metastatic carcinoma (stage 4) were more frequent in patient older than 40, Although not statistically significant. (14.5 versus 7.7%, p=0.9) and (11.1% versus 7.7%, p=1).
Conclusion: It seems that incidence of endometrial  cancer has increased among younger females. Although most of these patients had low stage cancers and grades, and low-risk endometrial carcinom and therefore, may have better prognosis.  
 

Keywords

References

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Jundishapur Scientific Medical Journal
Volume 13, Issue 4 - Serial Number 91
July and August 2014
Pages 438-444

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History

  • Receive Date: 03 November 2013
  • Revise Date: 19 May 2014
  • Accept Date: 25 June 2014

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