Comparison between the Effect of Hypertonic Saline and Ringer Lactate in Resuscitation of Trauma Patients with Hypovolemic Shock

Document Type : Original Article

Authors

1 Assistant Professor of General Surgery.Department of General Surgery, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

2 Associate Professor of General Surgery.Department of General Surgery, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

3 Resident of General Surgery.Department of General Surgery, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Abstract

Background and Objective: the most common cause of shock in surgical or trauma patients is blood loss due to bleeding. The usual treatment for this type of shock is the replacement of isotonic fluids. The aim of this project is to compare the effect of hypertonic saline (3.5%) and ringer lactate in the resuscitation of trauma patients with hypovolemic shock.
Subjects and Methods: In this double blind clinical trial study, using a simple random sampling, trauma patients referred to Ahwaz Golestan hospital emergency room, were divided into the case and control groups(85 cases VS.85 control). The group received a hypertonic saline solution 3.5% and intervention was done in the control group using the routine method of resuscitation, including administration of of ringer lactate.
Results: In this study. 170 patients (157 males and 13 females) were studied. The required time and the volume of the fluid intake to reach Blood pressure of 90 mmHg in the hypertonic-treated case group was significantly lower than the ringer lactate-treated control group. In a comparison between other variables, except serum sodium, 24 hr after the start of treatment, no significant difference was seen between the two groups.
Conclusion: At the start of the treatment for patients with patients with hypovolemic shock following trauma, the use of hypertonic salinewith a limited volume caused the reduced amount of fluid intake and the decreased the time of getting out of shock. Therefore, the use of hypertonic saline in patients with hypovolemic shock is recommended.

Keywords

References

 
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Jundishapur Scientific Medical Journal
Volume 15, Issue 4 - Serial Number 103
September and October 2017
Pages 391-396

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History

  • Receive Date: 22 March 2016
  • Revise Date: 24 July 2016
  • Accept Date: 28 August 2016

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