Comparison of Short Term Memory in Relapsing Remitting Multiple Sclerosis Patients with and without Depression and Normal Adults Resident in Ahwaz Province

Document Type : Original Article

Authors

1 Master of Science in Speech and language Pathology.Department of Speech Therapy, Faculty Member, School of Rehabilitation Sciences, Musculoskeletal Rehabilitation Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

2 Master of Science in Speech and language Pathology.Department of Speech and language Pathology, Special Education, Shahrekord, Shahrekord, Iran.

3 Associate Professor of Neurology.Department of Neurology, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

4 Master Student in Speech and language Pathology.Department of Speech Therapy, Faculty Member, School of Rehabilitation Sciences, Musculoskeletal Rehabilitation Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

5 Bachlor of science in Speech and language Pathology.Department of Speech Therapy, School of Rehabilitation Sciences, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

6 Master of Science in Speech and Language Pathology.Department of Speech Therapy,School of Rehabilitation Sciences, Tehran University of Medical Sciences,Tehran,Iran.

7 Master of Science in Speech and Language Pathology.Department of Speech Therapy, Faculty Member, School of Rehabilitation Sciences, Musculoskeletal Rehabilitation Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Abstract

Background and Objective: The neurobehavioral consequences of multiple sclerosis consistently include fatigue, clinical depression and cognitive dysfunction. The prevalence of severe depression in patients with multiple sclerosis is three times of the normal population. The researchers report that the prevalence of depression is approximately 27-54% in people with multiple sclerosis. Depression clearly impairs memory function. The purpose of this study was to determine whether there is a relationship between depression and short term memory in relapsing remitting multiple sclerosis patients.
Subjects and Methods: This was a cross-sectional study with 54 relapsing–remitting multiple sclerosis adult and 14 healthy controls. Beck Depression Inventory, digit span test from Wechsler Adult Intelligence Scale were applied from all participants. Data analysis was carried out using independent-t test by SPSS16 software.
Results: There was significant difference between patient and healthy groups on short term memory variable (P=0.05). However, but there was no significant difference between two groups of patients with and without (30 with depression and 24 without depression)depression on short term memory (P=0.82).
Conclusion: Cognitive deficits can be an early feature of MS, and can occur without clear correlation with other disease variables, such as duration or degree of physical disability, and general lesion load. According to the results of the study, cognitive deficits in MS patients is completely evident. On the other hand, Based on the findings of this study, depression  does not affect on cognitive functioning in relapsing-remmiting multiple sclerosis
 
 

Keywords

References

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Jundishapur Scientific Medical Journal
Volume 15, Issue 4 - Serial Number 103
September and October 2017
Pages 461-473

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History

  • Receive Date: 05 June 2016
  • Accept Date: 07 June 2016

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