Evaluation on the frequencies of extracolonic findings in virtual CT colonography in patients suspected to colorectal problems.

Document Type : Original Article

Authors

1 . School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

2 Assistant Professor of Radiology, Department of Radiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

Abstract

Introduction: Colon cancer is already one of the most prevalent cancers among different societies around the world for which some diagnostic modalities have been developed. With CT colonography there is the possibility of observing extracolonic findings which might have high clinical importance. Here we evaluated frequencies of extracolonic findings.
Methods: This cross sectional study was performed in 2016-2019 in Isfahan. 402 patients with colon problems which had been previously CT colonography imaging were entered. Data regarding to extracolonic findings were collected and analyzed.
Findings: We showed that there is a significant relation between total extracolonic findings and findings with moderate importance and age. In the way that these findings are more frequent in higher ages (p <0.001).
Discussion: Generally, in this article we indicated thatCT colonography in patients with colon problems especially patients with higher ages might lead to find extracolonic findings with high importance.
Keywords: Colon cancer, extracolonic finding, CT colonography.

Keywords


1-Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. Global cancer statistics. CA: a cancer journal for clinicians. 2011;61(2):69-90.
2-Arnold M, Sierra MS, Laversanne M, Soerjomataram I, Jemal A, Bray F. Global patterns and trends in colorectal cancer incidence and mortality. Gut. 2017;66(4):683-91.
3-Akhoond MR, Kazemnejad A, Hajizadeh E, GAnbary Motlagh A, Zali MR. Comparison of influential factors affecting survival of patients with colon and rectum cancer using competing risks model. Koomesh. 2011;12(2):119-28.
4-Gellad ZF, Provenzale D. Colorectal cancer: national and international perspective on the burden of disease and public health impact. Gastroenterology. 2010;138(6):2177-90.
5-Bishehsari F, Mahdavinia M, Vacca M, Malekzadeh R, Mariani-Costantini R. Epidemiological transition of colorectal cancer in developing countries: environmental factors, molecular pathways, and opportunities for prevention. World journal of gastroenterology: WJG. 2014;20(20):6055.
6-Durko L, Malecka-Panas E. Lifestyle modifications and colorectal cancer. Current colorectal cancer reports. 2014;10(1):45-54.
7-Powell LM, Nguyen BT. Fast-food and full-service restaurant consumption among children and adolescents: effect on energy, beverage, and nutrient intake. JAMA pediatrics. 2013;167(1):14-20.
8-Luo X, Stock C, Burwinkel B, Brenner H. Identification and evaluation of plasma microRNAs for early detection of colorectal cancer. PloS one. 2013;8(5):e62880.
9-Cairns SR, Scholefield JH, Steele RJ, Dunlop MG, Thomas HJ, Evans GD, et al. Guidelines for colorectal cancer screening and surveillance in moderate and high risk groups (update from 2002). Gut. 2010;59(5):666-89.
10-Quintero E, Castells A, Bujanda L, Cubiella J, Salas D, Lanas Á, et al. Colonoscopy versus fecal immunochemical testing in colorectal-cancer screening. New England Journal of Medicine. 2012;366(8):697-706.
11-Brenner H, Stock C, Hoffmeister M. Effect of screening sigmoidoscopy and screening colonoscopy on colorectal cancer incidence and mortality: systematic review and meta-analysis of randomised controlled trials and observational studies. Bmj. 2014;348:g2467.
12-Burling D, Standards ICfCc. CT colonography standards. Clinical radiology. 2010;65(6):474-80.
13-De Haan MC, Van Gelder RE, Graser A, Bipat S, Stoker J. Diagnostic value of CT-colonography as compared to colonoscopy in an asymptomatic screening population: a meta-analysis. European radiology. 2011;21(8):1747-63.
14-Pooler BD, Kim DH, Lam VP, Burnside ES, Pickhardt PJ. CT Colonography Reporting and Data System (C-RADS): benchmark values from a clinical screening program. American journal of roentgenology. 2014;202(6):1232-7.
15-Hara AK, Johnson CD, MacCarty RL, Welch TJ. Incidental extracolonic findings at CT colonography. Radiology. 2000;215(2):353-7.
16-Gluecker TM, Johnson CD, Wilson LA, MacCarty RL, Welch TJ, Vanness DJ, et al. Extracolonic findings at CT colonography: evaluation of prevalence and cost in a screening population. Gastroenterology. 2003;124(4):911-6.
17-HellstroĢˆm M, Svensson MH, Lasson A. Extracolonic and incidental findings on CT colonography (virtual colonoscopy). American Journal of Roentgenology. 2004;182(3):631-8.
18-Pickhardt PJ, Hanson ME, Vanness DJ, Lo JY, Kim DH, Taylor AJ, et al. Unsuspected extracolonic findings at screening CT colonography: clinical and economic impact1. Radiology. 2008;249(1):151-9.
19-Veerappan GR, Ally MR, Choi J-hR, Pak JS, Maydonovitch C, Wong RK. Extracolonic findings on CT colonography increases yield of colorectal cancer screening. American Journal of Roentgenology. 2010;195(3):677-86.
20-Kim DH, Pickhardt PJ, Taylor AJ, Leung WK, Winter TC, Hinshaw JL, et al. CT colonography versus colonoscopy for the detection of advanced neoplasia. New England journal of medicine. 2007;357(14):1403-12.