The effect of cochlear implant on auditory cortical plasticity in children with congenital deafness

Document Type : Original Article

Authors

1 Associate Professor of Otolaryngology.Department of Otolaryngology,School of Medicine, Ahvaz Jundishpur University of Medical Sciences, Ahvaz, Iran.

2 Khuzestan Cochlear Implant Center

Abstract

Background and Objects: A cochlear implant (CI) is now the standard treatment option for management of children with profound hearing loss. Cortical auditory evoked potential (CAEP) is a non-invasive procedure that can be used to objectively assess the maturation of the auditory cortex in children. The objective of current study was to investigate the effect of CI on central auditory plasticity in children through a novel CAEPs recording.
Subjects and Methods: In this analytic cross-sectional study, 42 children with profound prelingual hearing loss (age range: 2-3 years) participated. The CAEP responses were recorded across "before implantation ", "4-month post-implantation", and "8-month post-implantation" time points via HearLab system. For all children, the latency and wave amplitude of P1 wave was determined in response to /m/, /g/ and /s/ speech stimuli.
Results: The maen latency of P1 wave was significantly reduced for all speech stimuli after implantation compared to pre-CI time point (p <0.001). Similarly, the amplitude of P1 was significantly increased for after CI compared to pre-CI condition (p <0.001). Furthermore, the comparison of the latency and wave amplitude of the P1 in response to different speech stimuli demonstrated that the lowest latency and the largest amplitude was belong to /g/, and /m/ stimuli, respectively.
Conclusion: Our findings indicated that the latency and amplitude of CAEPs after implantation were reduced and increased, respectively. These results providing a document for increased neural activity (neuroplasticity) in auditory cortex region in children who underwent cochlear implantation at appropriate time.

Keywords

References

 
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Jundishapur Scientific Medical Journal
Volume 19, Issue 3 - Serial Number 126
September and October 2020
Pages 243-251

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History

  • Receive Date: 15 April 2020
  • Revise Date: 12 July 2020
  • Accept Date: 14 July 2020

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