Effect of eight weeks of aerobic interval training and urtica dioica supplement on some inflammatory indicators and glycemic control in men with type 2 diabetes

Document Type : Original Article


1 Department of Exercise Physiology, Kermanshah Branch, Islamic Azad University, Kermanshah, Iran.

2 Kermanshah Branch, Islamic Azad University, Kermanshah, Iran

3 Department of Physical Education and Sport Science, Kermanshah Branch, Islamic Azad University, Kermanshah, Iran.

4 Pediatric Gastroenterology and Hepatology Research Center, Zabol University of Medical Sciences, Zabol, Iran.


Background: Systemic inflammation is one of the factors affecting insulin resistance. The aim of study was to investigate the effect of aerobic interval training and use of nettle supplement on Inflammation Level and glycemic control in men with type II diabetes.
Methods: A quasi-experimental study, 40 male patients with type II diabetes (Age: 42.08 ± 3.99 years; body mass index: 27.01 ± 1.62 kg /m2) were randomly selected and divided into four groups: training, supplement, training + supplement and control groups. The aerobic interval training program was performed three days a week for eight weeks. Nettle tea was consumed 10 grams daily, 15 minutes before the three main meals. For statistical analysis, paired sample t-test and one-way ANOVA statistical methods were used (P≤0.05).
Results: There was a significant reduction was observed in FBS, HbA1C, IL-6 and CRP in training group and training + supplement compared to the control group. Also there was a significant decrease in FBS, IL-6 and CRP levels in supplement group compared to the control group (P <0.05). Also, HbA1C was significantly lower in the training + supplement group than the supplement group (P = 0.002).
Conclusion: Both interventional aerobic interval training and nettle supplementation seem to play a beneficial role in reducing inflammation and glycemic control, and the combination of the two methods is more effective in glycemic control in patients with type 2 diabetes.


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