Investigation Moderator Effect of Body composition and gender on Improvement of Sleep Quality, Sleepiness and Quality of Life during Aerobic Interval Training program in People with Multiple Sclerosis

Document Type : Original Article

Authors

1 Department of Physical Education, Abadan branch, Islamic Azad University, Abadan, Iran

2 PhD Student of Physical Education and Sport Sciences.Department of Physical Education & Sport Sciences, Faculty of Humanities, Tarbiat Modares University, Tehran, Iran.

3 Assistant Professor of Sport Physiology.Department of Sports Physiology, Shahid Chamran University of Ahvaz, Ahvaz, Iran.

4 Department of Sports Physiology, Shahid Chamran University of Ahvaz, Ahvaz, Iran

Abstract

Background and Objective: Because of the scarcity of data available from effect of weight and gender on beneficial effect of exercise training, it is unknown whether overweight people with multiple sclerosis (MS) can improve their the sleep quality, sleepiness and quality of life as much as normal weight people and whether women can improve as much as men in response to exercise training. Therefore, this study aimed to investigate the effects of gender and weight on the improvement of quality of sleep and life response to exercise training in people with MS.
Methods: Thirty-six persons with MS were recruited to participate in aerobic interval exercise training based on body weight status and gender, and divided into four groups include normal weight-male, normal weight-female, overweight-male and overweight-female. The exercise included 8-weeks of interval exercise at 60-75% Wattpeak. Sleep quality, sleepiness and quality of life were measured before and following the 8-week period.
Results: All indicators showed significant improvement after exercise training. There were significant weight effects for improvement quality of sleep and life during exercise training. There were no significant gender and weight-gender interaction effects for improvement quality of sleep and life during exercise training. No significant weight, gender and interaction effect was found for sleepiness indicator during exercise training. Weight loss significantly associated with improvement of quality of life and sleep.
Conclusion: The results confirm that exercise is an effective therapeutic method for improving quality of life and sleep, which dependent of body composition in people with MS.

Keywords

References

1-Motl RW, Pilutti LA. Is physical exercise a multiple sclerosis disease modifying treatment? Expert review of neurotherapeutics. 2016;16(8):951-60.
2-Motl RW, Sandroff BM, Kwakkel G, Dalgas U, Feinstein A, Heesen C, et al. Exercise in patients with multiple sclerosis. The Lancet Neurology. 2017;16(10):848-56.
3-McDonald WI, Compston A, Edan G, Goodkin D, Hartung HP, Lublin FD, et al. Recommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the diagnosis of multiple sclerosis. Annals of neurology. 2001;50(1):121-7.
4-Latimer-Cheung AE, Pilutti LA, Hicks AL, Ginis KAM, Fenuta AM, MacKibbon KA, et al. Effects of exercise training on fitness, mobility, fatigue, and health-related quality of life among adults with multiple sclerosis: a systematic review to inform guideline development. Archives of physical medicine and rehabilitation. 2013;94(9):1800-28. e3.
5-Pilutti LA, Greenlee TA, Motl RW, Nickrent MS, Petruzzello SJ. Effects of exercise training on fatigue in multiple sclerosis: a meta-analysis. Psychosomatic medicine. 2013;75(6):575-80.
6-Kallweit U, Baumann CR, Harzheim M, Hidalgo H, Pöhlau D, Bassetti CL, et al. Fatigue and sleep-disordered breathing in multiple sclerosis: a clinically relevant association? Multiple sclerosis international. 2013;20(13).
7-Dias RA, Hardin KA, Rose H, Agius MA, Apperson ML, Brass SD. Sleepiness, fatigue, and risk of obstructive sleep apnea using the STOP-BANG questionnaire in multiple sclerosis: a pilot study. Sleep and Breathing. 2012;16(4):1255-65.
8-Aburub A, Khalil H, Al-Sharman A, Alomari M, Khabour O. The association between physical activity and sleep characteristics in people with multiple sclerosis. Multiple sclerosis and related disorders. 2017;12:29-33.
9-Bamer AM, Johnson K, Amtmann D, Kraft G. Prevalence of sleep problems in individuals with multiple sclerosis. Multiple Sclerosis Journal. 2008;14(8):1127-30.
10-Siengsukon CF, Aldughmi M, Kahya M, Bruce J, Lynch S, Ness Norouzinia A, et al. Randomized controlled trial of exercise interventions to improve sleep quality and daytime sleepiness in individuals with multiple sclerosis: A pilot study. Multiple Sclerosis Journal–Experimental, Translational and Clinical. 2016;2:1-15.
11-Nascimento CMC, Ayan C, Cancela JM, Gobbi LTB, Gobbi S, Stella F. Effect of a multimodal exercise program on sleep disturbances and instrumental activities of daily living performance on P arkinson's and A lzheimer's disease patients. Geriatrics & gerontology international. 2014;14(2):259.
12-Morgan K. Daytime activity and risk factors for late‐life insomnia. Journal of sleep research. 2003;12(3):231-8.
13-Mokhtarzade M, Ranjbar R, Majdinasab N. The effect of interval aerobic training on some functional factors, quality of life, fatigue and sleep in women with multiple sclerosis. Daneshvar Pezeshki Journal. 2016;125:67-76.
14-Mokhtarzade M, Motl R, Negaresh R, Zimmer P, Khodadoost M, Baker JS, et al. Exercise-induced changes in neurotrophic factors and markers of blood-brain barrier permeability are moderated by weight status in multiple sclerosis. Neuropeptides. 2018;70:93-100.
15-Negaresh R, Motl R, Mokhtarzade M, Ranjbar R, Majdinasab N, Khodadoost M, et al. Effect of Short-Term Interval Exercise Training on Fatigue, Depression and Fitness in Normal Weight vs. Overweight person with Multiple Sclerosis. EXPLORE. 2018; 15(2):134-141.
16-Mokhtarzade M, Ranjbar R, Majdinasab N, Patel D, Shamsi MM. Effect of aerobic interval training on serum IL-10, TNFα, and adipokines levels in women with multiple sclerosis: possible relations with fatigue and quality of life. Endocrine. 2017:1-10.
17-Storer TW, Davis JA, Caiozzo VJ. Accurate prediction of VO2max in cycle ergometry. Medicine and science in sports and exercise. 1990;22(5):704-12.
18-Sawka MN, Foley ME, Pimental NA, Toner MM, Pandolf KB. Determination of maximal aerobic power during upper-body exercise. Journal of applied Physiology. 1983;54(1):113-7.
19-Buysse DJ, Reynolds CF, Monk TH, Berman SR, Kupfer DJ. The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research. Psychiatry research. 1989;28(2):193-213.
20-Johns MW. A new method for measuring daytime sleepiness: the Epworth sleepiness scale. sleep. 1991;14(6):540-5.
21-Usefy A, Ghassemi GR, Sarrafzadegan N, Mallik S, Baghaei A, Rabiei K. Psychometric properties of the WHOQOL-BREF in an Iranian adult sample. Community mental health journal. 2010;46(2):139-47.
22-Pilutti L, Dlugonski D, Sandroff B, Klaren R, Motl R. Randomized controlled trial of a behavioral intervention targeting symptoms and physical activity in multiple sclerosis. Multiple Sclerosis Journal. 2014;20(5):594-601.
23-Yang P-Y, Ho K-H, Chen H-C, Chien M-Y. Exercise training improves sleep quality in middle-aged and older adults with sleep problems: a systematic review. Journal of physiotherapy. 2012;58(3):157-63.
24-Majdinasab N, Motl RW, Mokhtarzade M, Zimmer P, Ranjbar R, Keytsman C, et al. Acute responses of cytokines and adipokines to aerobic exercise in relapsing vs. remitting women with multiple sclerosis. Complementary therapies in clinical practice. 2018; ;31:295-301.
25-Marck CH, Neate SL, Taylor KL, Weiland TJ, Jelinek GA. Prevalence of comorbidities, overweight and obesity in an international sample of people with multiple sclerosis and associations with modifiable lifestyle factors. PloS one. 2016;11(2):e0148573.
26-Munger KL, Bentzen J, Laursen B, Stenager E, Koch-Henriksen N, Sørensen TI, et al. Childhood body mass index and multiple sclerosis risk: a long-term cohort study. Multiple Sclerosis Journal. 2013;19(10):132.
27-Munger KL, Chitnis T, Ascherio A. Body size and risk of MS in two cohorts of US women. Neurology. 2009;73(19):1543-50.
28-Negaresh R, Motl RW, Mokhtarzade M, Dalgas U, Patel D, Shamsi MM, et al. Effects of Exercise Training on Cytokines and Adipokines in Multiple Sclerosis: A Systematic Review. Multiple sclerosis and related disorders. 2018; 24:91-100.
29-Bollaert RE, Motl RW. Physical and Cognitive Functions, Physical Activity, and Sedentary Behavior in Older Adults With Multiple Sclerosis. Journal of geriatric physical therapy (2001). 2017.
30-McCarty DE, Chesson Jr AL, Jain SK, Marino AAJSmr. The link between vitamin D metabolism and sleep medicine. 2014;18(4):311-9.
31-Lobentanz I, Asenbaum S, Vass K, Sauter C, Klösch G, Kollegger H, et al. Factors influencing quality of life in multiple sclerosis patients: disability, depressive mood, fatigue and sleep quality. Acta Neurologica Scandinavica. 2004;110(1):6-13.
Jundishapur Scientific Medical Journal
Volume 18, Issue 5 - Serial Number 122
January and February 2020
Pages 491-506

Files

History

  • Receive Date: 01 October 2019
  • Revise Date: 27 October 2019
  • Accept Date: 14 December 2019

Share

How to cite

Statistics