Effect of a 5-Day Vitamin C Supplements on Immunological Stress Caused by an Aerobic Exercise Session in Young Women

Document Type : Original Article

Authors

1 MSc Student in Exercise Physiology.Islamic Azad University, Science and Research Bushehr, Bushehr, Iran.

2 PhD in Exercise Physiology.Department of Exercise Physiology, Islamic Azad University, Science and Research Department of Physical Education in Bushehr, Bushehr, Iran.

3 PhD in Exercise Physiology. Department of Exercise Physiology, Islamic Azad University, Science and Research Department of Physical Education in Bushehr, Bushehr, Iran.

Abstract

Background and Objective: Physical activity and some antioxidants, such as vitamin C, can affect the immune system. This The current research attempts to determine the immune system reaction following consumption of vitamin C after an aerobic physical activity.
Subjects and Methods: In the present experimental work, 24 females aged 32 y were selected by random sampling and divided into two 12-subjects groups, first group (vitamin C) and the second group (placebo). In the pre-test, the serum baseline measurements for IgG and IgA were made for both groups. Then, 500 mg of vitamin C was given to the experimental group once daily for 5 days. After five days, blood samples were taken from both groups. Finally, on the 6th day immediately blood sampling was performed after aerobic physical exercise (Bruce test). And then was taken to the lab by immunological examination after analyzing the data, the required information was collected.
Results: The results showed that after aerobic activity level of IgG and IgA were significantly higher (P <0.05), while plasma cortisol levels were significantly lower (P <0.05) in the vitamin C group compared to the placebo group.
Conclusion: The consumption of vitamin C following aerobic exercise has an effect on the levels of A and G immunoglobulin’s and serum cortisol levels, and the repressive effects of the exercise-induced immune system are somewhat reduced.

Keywords

References

1-Gleeson M. Immunological aspects of sport nutrition. Immunology and cell biology. 2016;94(2):117.
2-Peake JM, Neubauer O, Walsh NP, Simpson RJ. Recovery of the immune system after exercise. Journal of Applied Physiology. 2016:jap. 00622.2016.
3-Nieman DC. Exercise effects on systemic immunity. Immunology and Cell Biology. 2000;78(5):496-501.
4-Shirvani H, Ghahreman-Tabrizi K, Sobhani V. Effects of high intensity intermittent exercise on serum response in Immunoglobulin’s and Complement system youth soccer players. Journal of Birjand University of Medical Sciences. 2013;;20(3):233-43.
5-Liew FY, Russell SM, Appleyard G, Brand CM, Beale J. Cross‐protection in mice infected with influenza A virus by the respiratory route is correlated with local IgA antibody rather than serum antibody or cytotoxic T cell reactivity. European journal of immunology. 1984;14(4):350-6.
6-Tomasi TB, Trudeau FB, Czerwinski D, Erredge S. Immune parameters in athletes before and after strenuous exercise. Journal of clinical immunology. 1982;2(3):173-8.
7-Nehlsen-Cannarella SL, Nieman DC, Fagoaga OR, Kelln WJ, Henson DA, Shannon M, et al. Saliva immunoglobulins in elite women rowers. European Journal of Applied Physiology. 2000;81(3):222-8.
8-Libicz S, Mercier B, Bigou N, Le Gallais D, Castex F. Salivary IgA response of triathletes participating in the French Iron Tour. International journal of sports medicine. 2006;27(05):389-94.
9-Allgrove JE, Gomes E, Hough J, Gleeson M. Effects of exercise intensity on salivary antimicrobial proteins and markers of stress in active men. Journal of Sports Sciences. 2008;26(6):653-61.
10-Li T-L, Gleeson M. The effect of single and repeated bouts of prolonged cycling and circadian variation on saliva flow rate, immunoglobulin A and α-amylase responses. Journal of Sports Sciences. 2004;22(11-1):1015-24.
11-Ljungberg G, Ericson T, Ekblom B, Birkhed D. Saliva and marathon running. Scandinavian journal of medicine & science in sports. 1997;7(4):214-9.
12-Tsubakihara T, Umeda T, Takahashi I, Matsuzaka M, Iwane K, Tanaka M, et al. Effects of soccer matches on neutrophil and lymphocyte functions in female university soccer players. Luminescence. 2013;28(2):129-35.
13-BRATTHALL D, WIDERSTRÖM L. Ups and downs for salivary IgA. European Journal of Oral Sciences. 1985;93(2):128-34.
14-Farzanaki P, Azarbayjani M, Rasaee M, Jourkesh M, Ostojic S, Stannard S. Salivary immunoglobulin A and cortisol response to training in young elite female gymnasts. Braz J Biom. 2008;2:252-8.
15-Iqbal K, Khan A, Khattak MMAK. Biological significance of ascorbic acid (Vitamin C) in human health–a review. Pakistan Journal of Nutrition. 2004;3(1):5-13.
16-Krause R, Patruta S, Daxböck F, Fladerer P, Biegelmayer C, Wenisch C. Effect of vitamin C on neutrophil function after high‐intensity exercise. European journal of clinical investigation. 2001;31(3):258-63.
17-Shirvani H, Sobhani V. The study of immunoglobulin A, G and cortisol serum response in two consecutive soccer match and vitamin C supplements. Razi Journal of Medical Sciences. 2015;22(133):70-9.
18-Nieman DC, Peters EM, Henson DA, Nevines EI, Thompson MM. Influence of vitamin C supplementation on cytokine changes following an ultramarathon. Journal of Interferon & Cytokine Research. 2000;20(11):1029-35.
19-Nieman DC, Bishop NC. Nutritional strategies to counter stress to the immune system in athletes, with special reference to football. Journal of sports sciences. 2006;24(07):763-72.
20-Peters E, Anderson R, Theron A. Attenuation of increase in circulating cortisol and enhancement of the acute phase protein response in vitamin C-supplemented ultramarathoners. International journal of sports medicine. 2001;22(02):120-6.
21-Nieman DC, Henson DA, Butterworth DE, Warren BJ, Davis JM, Fagoaga OR, et al. Vitamin C supplementation does not alter the immune response to 2.5 hours of running. International journal of sport nutrition. 1997;7(3):173-84.
22-Thompson D, Williams C, Kingsley M, Nicholas C, Lakomy H, McArdle F, et al. Muscle soreness and damage parameters after prolonged intermittent shuttle-running following acute vitamin C supplementation. International journal of sports medicine. 2001;22(01):68-75.
23-Tanaka H, Matsuda T, Miyagantani Y, Yukioka T, Matsuda H, Shimazaki S. Reduction of resuscitation fluid volumes in severely burned patients using ascorbic acid administration: a randomized, prospective study. Archives of Surgery. 2000;135(3):326-31.
24-Alikarami H, Nikbakht M, V V-D, Ghalavand A. Effect of 8 weeks of continuous moderate intensity aerobic training on iron status in club-level football players. Horizon of Medical Sciences. 2017;23(2):129-33.
25-Hasanloei F, Dodman MK, Kalantar J. Effect of vitamin C intake following exhaustive aerobic exercise on serum immunoglobulins A and G in karate athletes. International Journal of Sport Studies. 2013;3(3):327-33.
26-Shahrokhian S, Shakerian S. Functional test, anthropometric and laboratory of sport physiology: Sokhanvaran; 2017.
27-Gleeson M. Immune function in sport and exercise. Journal of applied physiology. 2007;103(2):693-9.
28-Jakemanl P, Maxwell S. Effect of antioxidant vitamin supplementation on muscle function after eccentric exercise. European journal of applied physiology and occupational physiology. 1993;67(5):426-30.
29-Andersen HR, Nielsen JB, Nielsen F, Grandjean P. Antioxidative enzyme activities in human erythrocytes. Clinical chemistry. 1997;43(4):562-8.
Jundishapur Scientific Medical Journal
Volume 16, Issue 5 - Serial Number 110
November and December 2017
Pages 535-545

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History

  • Receive Date: 16 May 2016
  • Revise Date: 09 August 2017
  • Accept Date: 12 August 2017

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