Relationship of Prostate Volume and Serum Prostate-specific Antigen with Body Mass Index in Men Over 40 Years Old

Document Type : Original Article

Authors

1 Department of Radiology, Golestan Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

2 Associate Professor of Radiology, Department of Radiology, School of Medicine, Imam Khomeini Hospital, Golestan Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

3 Assistant Professor of Uro-oncology, Department of Urology, School of Medicine, Golestan Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

4 Assistant Professor of Radiology, Department of Radiology, School of Medicine, Golestan Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

10.61186/jsmj.22.5.2

Abstract

Background and Objectives Prostate cancer is the second most common cancer in men worldwide and the third leading cause of cancer-related death in men after lung and colon cancer. The present study aimed to assess the relationship of prostate volume and serum prostate-specific antigen (PSA) with body mass index (BMI) in men over 40 years old in Ahvaz.
Subjects and Methods This descriptive-analytical study was conducted on apparently healthy men over 40 years of age. Parameters, such as age, BMI, prostate volume, and PSA level, were checked in all subjects. The relationship between age, BMI, prostate volume, and PSA level in men over 40 was evaluated as prostate cancer diagnosis parameters.
Results The mean age of subjects was 58.61±10.01 years. A significant relationship was observed between BMI and prostate volume (P=0.019), BMI and PSA level (P=0.001), prostate volume and age of patients (P<0.001), and age and PSA level (r=0.821; P<0.001). People with higher BMI had higher mean prostate volume and PSA levels compared to those with lower BMI. An increase in age was significantly associated with increasing prostate volume and PSA level. In general, there was no correlation between prostate volume and PSA level (P=0.37).
Conclusion As evidenced by the results of this hospital study, an increase in age and BMI are positively related to PSA concentration and prostate volume; nonetheless, no correlation was observed between PSA and prostate volume. BMI and age may be better parameters to estimate PSA concentration and prostate volume.

Keywords

Main Subjects

References

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Jundishapur Scientific Medical Journal
Volume 22, Issue 5 - Serial Number 146
November and December 2024
Pages 290-298

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History

  • Receive Date: 02 September 2023
  • Revise Date: 23 December 2023
  • Accept Date: 02 January 2024

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