Investigating the Risk Factors of Congenital Heart Diseases in Newborns Admitted to Amir al-Momenin Hospital in Semnan from 2020-2021

Document Type : Original Article

Authors

1 Assistant Professor of Pediatric Endocrinology & Metabolism.Department of Pediatrics, School of Medicine Semnan University of Medical Sciences.

2 Assistant Professor of Cardiology Department of Pediatrics, School of Medicine Semnan University of Medical Sciences

3 Assistant Professor of Pediatric Infectious DiseaseDepartment of Pediatrics, School of MedicineSemnan University of Medical Sciences.

4 Assistant Professor of Epidemiology, Department of Public Health, Behbahan Faculty of Medical Sciences, Behbahan, Iran.

5 Medical student of Semnan University of Medical Sciences.

10.61186/jsmj.22.5.10

Abstract

Introduction: Congenital heart defects refer to conditions that affect the structure and function of a newborn’s heart. The aim of this study was to investigate the prevalence and risk factors of congenital heart diseases in hospitalized infants in the neonatal intensive care unit of Amiralmomenin Hospital in Semnan.
Methods: In this study, 300 medical records of hospitalized infants who underwent echocardiography in the neonatal intensive care unit of Amiralmomenin Hospital in Semnan during 2020-2021 were reviewed. The overall prevalence of congenital heart diseases and their types (ASD/VSD/PDA/TOF) were determined, and the association of study variables (infant gender, gestational age, maternal age, infant weight, parental family history, medication use during pregnancy, and history of heart disease and gestational diabetes) with congenital heart disease was evaluated.
Results: The results showed that out of the total 300 hospitalized infants who underwent echocardiography, 132 infants (44%) were diagnosed with congenital heart disease. PDA and VSD were the most common types of congenital heart diseases with a prevalence of 8.56% and 5.23%, respectively.

Conclusion: According to the results, there was a significant association between congenital heart disease and diabetes, hypertension, as well as medication use during pregnancy and family history of heart disease , infant gender, gestational age, and weight did not show a significant association. However, there was a significant association between the type of congenital heart disease and gestational age and infant weight, with an increase in gestational age and infant weight leading to a decrease in the prevalence of congenital heart disease

Highlights

Parisa Tajdini [PumMed] [Google Scholar]

Soodeh Hooshmandi [PumMed] [Google Scholar]

Morteza Rezaei [PumMed] [Google Scholar]

 Sajad Rahimi [PumMed] [Google Scholar]

 Fatemeh Alijan [PumMed] [Google Scholar]

Keywords

Main Subjects

References

[1] Saleh MK, Hasan AS, Noaman NG. The positivity rate of Epstein-Barr virus anti-viral capsid antigen IgG among children with infectious mononucleosis in Diyala-Iraq. GSC Biological and Pharmaceutical Sciences. 2020;13(3):19-24. [DOI:10. 30574/gscbps.2020.13.3.0392]
[2] Reefhuis J, Gilboa SM, Anderka M, Browne ML, Feldkamp ML, Hobbs CA, et al. The national birth defects prevention study: a review of the methods. Birth Defects Res A Clin Mol Teratol. 2015;103(8):656-69. [DOI: 10.1002/bdra.23384] [PMID] [PMCID]
[3] Patorno E, Huybrechts KF, Bateman BT, Cohen JM, Desai RJ, Mogun H, et al. Lithium use in pregnancy and the risk of cardiac malformations. N Engl J Med. 2017;376(23):2245-54. [DOI: 10.1056/NEJMoa1612222] [PMID] [PMCID]
[4] Cai G-j, Sun X-x, Zhang L, Hong Q. Association between maternal body mass index and congenital heart defects in offspring: a systematic review. Am J Obstet Gynecol. 2014;211(2):91-117. [DOI: 10.1016/j.ajog.2014.03.028] [PMID]
[5] Amel-Shahbaz S, Behjati-Ardakani M, Namayandeh SM, Vafaeenasab M, Andishmand A, Moghimi S, et al. The epidemiological aspects of congenital heart disease in central and southern district of Iran. Adv Biomed Res. 2014;3:233. [DOI: 10.4103/2277-9175.145732] [PMID]
[6] Simeone RM, Oster ME, Cassell CH, Armour BS, Gray DT, Honein MA. Pediatric inpatient hospital resource use for congenital heart defects. Birth Defects Res A Clin Mol Teratol. 2014;100(12):934-43. [DOI: 10.1002/bdra.23262] [PMID] [PMCID]
[7] Liu X, Liu G, Wang P, Huang Y, Liu E, Li D, et al. Prevalence of congenital heart disease and its related risk indicators among 90 796 Chinese neonates aged less than 6 months in Tianjin. Int J Epidemiol. 2015;44(3):884-93. [DOI: 10.1093/ije/dyv107] [PMID]
[8] Ou Y, Mai J, Zhuang J, Liu X, Wu Y, Gao X, et al. Risk factors of different congenital heart defects in Guangdong, China. Pediatr Res. 2016;79(4):549-58. [DOI: 10.1038/pr.2015.264] [PMID]
[9] Mohsenzadeh A, Saket S, Ahmadipour S, Baharvand B. [Prevalence and types of congenital heart disease in babies born in the city of Khorramabad (2007-2011) (Persian)]. Yafte. 2014;15(5):23-9. [Link]
[10] Dehghani A, Soodejani M, Lotfi MH, Fallahzadeh H, Noori M. [Study of Prevalence &Risk Factors of Congenital Heart Defect (Persian)]. J Tolooebehdasht Sci. 2017;16(3):106-16. [Link]
[11] Sabzehei MK, Tanasan A, Shokouhi M, Basiri B. [The prevalence and risk factors of congenital heart disease and its outcome in infants admitted to nicu of besat hospital of hamadan in 2012-2017. studies in medical science (Persian)]. The journal of urmia university of medical scinces. 2019;30(7):565-74. [Link]
[12] Qu Y, Liu X, Zhuang J, Chen G, Mai J, Guo X, et al. Incidence of congenital heart disease: the 9-year experience of the Guangdong registry of congenital heart disease, China. PLoS One. 2016;11(7):e0159257. [DOI: 10.1371/journal.pone. 0159257] [PMID] [PMCID]
[13] Sun P-F, Ding G-C, Zhang M-Y, He S-N, Gao Y, Wang J-H. Prevalence of congenital heart disease among neonates from 2012 to 2014 in Langfang, China. Chin Med J (Engl). 2017;130(9):1069-73. [DOI: 10.4103/0366-6999.204923]
[PMID] [PMCID]
[14] Pei L, Kang Y, Zhao Y, Yan H. Prevalence and risk factors of congenital heart defects among live births: a population-based cross-sectional survey in Shaanxi province, Northwestern China. BMC Pediatr. 2017;17(1):18. [DOI: 10.1186/s12887-017-0784-1] [PMID] [PMCID]
[15] Yokouchi-Konishi T, Yoshimatsu J, Sawada M, Shionoiri T, Nakanishi A, Horiuchi C, et al. Recurrent congenital heart diseases among neonates born to mothers with congenital heart diseases. Pediatr Cardiol. 2019;40(4):865-70. [DOI: 10. 1007/s00246-019-02083-6] [PMID]
Jundishapur Scientific Medical Journal
Volume 22, Issue 5 - Serial Number 146
November and December 2024
Pages 607-618

Files

History

  • Receive Date: 08 August 2023
  • Revise Date: 11 December 2023
  • Accept Date: 19 December 2023

Share

How to cite

Statistics