The Effect of Radiation Therapy to the Neck on the Quality of Voice

Document Type : Original Article

Authors

1 Associate Professor of Otolaryngology.Department of Otolaryngology,School of Medicine, Ahvaz Jundishpur University of Medical Sciences, Ahvaz, Iran.

2 Residentof Otolaryngology. Department of Otolaryngology,School of Medicine, Ahvaz Jundishpur University of Medical Sciences, Ahvaz, Iran.

3 Medical Student Shiraz University of Medical Sciences(international br)

4 Speech Therapist. Apadana Hospital

Abstract

Background and Objective: The aim of this study is the assessment of quality of voice in patients who had radiotherapy to the neck in regards to parameters such as basic frequency, perturbation, and percent voiced, to investigate the effect of radiotherapy on patients' quality of voice.
Subjects and Methods:  34 patients with head and neck cancer that received radiation therapy as their only form of treatment underwent a voice analysis. The voice analysis consisted of an audio recording made to include three samples of a sustained phonation of the vowel/a/.  Volume Unit Meter was monitored to peak at 0 during a practice count to 10. The best phonation of the three samples was played back for voice analyzer. Up to 9 seconds of the sustained vowel sound /a/ was analyzed for perturbation, percent of voicing and average fundamental frequency. This analysis was repeated 6 months following the completion of radiotherapy.
Results: The voice parameters of 15 patients with laryngeal tumors re analyzed separately from the 19 patients with non-laryngeal tumors. Patients with laryngeal tumors had 12% increase in the  fundamental frequency, 14% improvement in perturbation and 52% improvement in percent voiced. Changes in percent voiced were statistically significant. Patients with non-laryngeal tumors had 42 % increase in the  fundamental frequency compared to the baseline frequency before radiotherapy, 14% improvement in perturbation and 52% improvement in percent voiced. Patients with non larygeal head and neck tumors had 42% improvement in basic frequency compared to the baseline frequency before radiotherapy. Conclusion: Radiotherapy has significantly improved the voice quality of patients with early stage of laryngeal tumors.

Keywords

References

1-Lin E, Hwang TZ, Hornibrook J, Ormond T. Voice of postradiotherapy nasopharyngeal carcinoma patients: evidence of vocal tract effect. J Voice 2008;22(3):351-64.
2-Nakamura K, Shioyama Y, Kawashima M, Saito Y, Nakamura N, Nakata K, et al. Multi-institutional analysis of early squamous cell carcinoma of the hypopharynx treated with radical radiotherapy. Int J Radiat Oncol Biol Phys. 2006;65(4):1045-50.
3-Tamura E, Kitahara S, Ogura M, Kohno N. Voice quality after laser surgery or radiotherapy for T1a glottic carcinoma. Laryngoscope 2003;113(5):910-4.
4-Yamazaki H, Inoue T, Tanaka E, Yoshida K, Imai A, Yoshioka Y, et al. Radiation and low dose adriamycin for the treatment of carcinoma of the hypopharynx. Anticancer Res 2000;20(6C):4713-20.
5-Mawson A, Berry K, Murray C, KHayward M. Voice hearing within the context of hearers' social worlds: An interpretative phenomenological analysis. Psychol Psychother. 2010.
6-Evitts PM, Kasapoglu F, Demirci U, Miller JS. Communication adjustment of patients with a laryngectomy in Turkey: Analysis by type of surgery and mode of speech. Psychol Health Med 2011;16(6):650-60. 7-Li Y, Zhang XB. [Longterm effect of phonomirsurgery on early glottic cancer]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2006;41(6):443-6. [Article in Chinese]
8-Sato K, Nakashima T. Effect of irradiation on the human laryngeal glands. Ann Otol Rhinol Laryngol 2008;117(10):734-9.
9-Van Loon Y, Sjögren EV, Langeveld TP, Baatenburg de Jong RJ, Schoones JW, van Rossum MA. Functional outcomes after radiotherapy or laser surgery in early glottic carcinoma: A systematic review. Head Neck 2012;34(8):1179-89.
10-Stoicheff ML, Ciampi A, Passi JE, Fredrickson JM. The irradiated larynx and voice: a perceptual study. J Speech Hear Res 1983;26(4):482-5.
11-Karim AB, Snow GB, Siek HT, Njo KH. The quality of voice in patients irradiated for laryngeal carcinoma. Cancer 1983;51(1):47-9.12-Hoyt DJ, Lettinga JW, Leopold KA, Fisher SR. The effect of head and neck radiation therapy on voice quality. Laryngoscope 1992;102(5):477-80.
13-Casiano RR, Cooper JD, Lundy DS, Chandler JR. Laser cordectomy for T1 glottic carcinoma: a 10-year experience and videostroboscopic findings. Otolaryngol Head Neck Surg 1991;104(6):831-7.
 
Jundishapur Scientific Medical Journal
Volume 11, Issue 5
July and August 2017
Pages 519-525

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History

  • Receive Date: 09 November 2011
  • Revise Date: 26 May 2012
  • Accept Date: 29 May 2012

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