The prevalence of depression in patients with Parkinson'sdisease and its relationship with clinical and demographic variables at Ahwaz's Golestan Hospital

Document Type : Original Article

Authors

1 Department of Psychiatry, School of Medicine, Ahvaz Jundishapur University of Medical Sciences

2 Assisstant Professor, Psychiatry Department, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

3 Department of Neurology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences

Abstract

Abstract
Introduction:
The prevalence of depression in Parkinson's patients is significantly higher than in the general population or patients with general medical status other than Parkinson's. Considering the importance of depression and its preventive and therapeutic potential in patients with Parkinson's disease and the possibility of improving the quality of life in these patients as well as the lack of such a study in Ahvaz, this study aimed to investigate the prevalence and effective factors in depression in patients with Parkinson's disease.
Material and Method:
This study was cross-sectional and descriptive-analytic that was performed on 36 patients referred to the Parkinson's disease association of Ahvaz Golestan Hospital in 2017(march to September). The patients are analyzed by demographic questionnaire and Beck depression test. Finally, all analyses were performed using SPSS software version 22.
Results:
Of the 36 patients with Parkinson's disease, 4 (11.1%) had no depression, 9 (25%) had borderline symptoms, 8 (22.2%) had mild depression, 10 (27.8%) had moderate depression and 5 Patients (13.9%) had severe depression. In general, mean depression was 20.25±9. depression was higher in married people and urban population and old higher61.(p < 0/05)
Conclusion:
Overall mean depression in Parkinson's patients was 20.25±9 which was in the range of moderate depression and was not correlated with job, body mass, education level, income, duration of illness and occupation but marital, age And the location was related
Keywords: Depression, Parkinson'sdisease,.

Keywords


1-Chen ML, Chang HK and Yeh CH. Anxiety and depression in Taiwanese cancer patients with and without pain. J Adv Nurs 2000; 32(4): 944-51.
2-Rossi, A., Berger, K., Chen, H., Leslie, D., Mailman, R. B., & Huang, X. (2018). Projection of the prevalence of Parkinson’s disease in the coming decades: Revisited. MovementDisorders, 33(1), 156–159.
3-Bitner A, Zalewski P, Klawe JJ, Newton JL. Drug Interactions in Parkinson's Disease: Safety of Pharmacotherapy for Arterial Hypertension.Drugs Real World Outcomes.2015;2(1):1-12.
4-Csoti I, Jost WH, Reichmann H. Parkinson's disease between internal medicine and neurology. J Neural Transm (Vienna). 2016;123(1):3-17.
5-Aarsland D, Larsen JP, Karlsen K, Lim NG, Tandberg E. Mental symptoms in parkinson's disease are important contributors to caregiver distress. Int J Geriatr Psychiatry 1999; 14(10): 866-74.
6-Angelino AF and Treisman GJ. Major depression and demoralization in cancer patients: diagnostic and treatment considerations. SupportCareCancer2001; 9(5): 344-9.
7-Clyburn LD, Stones MJ, Hadjistavropoulos T, Tuokko H. Predicting caregiver burden and depression in Alzheimer's disease. J Gerontol B Psychol Sci Soc Sci 2000; 55(1): S2-13.
8-Thommessen B, Aarsland D, Braekhus A, Oksengaard AR, Engedal K, Laake K. The psychosocial burden on spouses of the elderly with stroke, dementia and parkinson's disease. Int J Geriatr Psychiatry 2002; 17(1): 78-84.
9-Lee PWH, Chang PCM, Fung ASM, Leung PWL. Issues in the care of elderly patients with Parkinson's disease: cognitive impairment, daily life adjustment, behavioral/emotional problems and caregiver burden. J HK Coll Psychiatr 1994; 4: 21-7.
10-Shi-Shuang Cui, Juan-Juan Du, Rao Fu, Yi-Qi Lin, Pei Huang, Ya-Chao He, Chao Gao, Hua-Long Wang and Sheng-Di Chen. Prevalence and risk factors for depression and anxiety in Chinese patients with Parkinson disease. Cui et al. BMC Geriatrics .2017;17:270.
11-Schwartz L, Lander M and Chochinov HM. Current management of depression in cancer patients. Oncology 2002; 16(8): 1102-10
12-ASPE research notes. Washington (DC): Office of the Assistant Secretary for Planning and Evaluation, U.S. Department of Health and Human Services; c1993 Apr. [cited 2005 Nov 15]. Available from: URL; http://aspe.hhs.gov/daltcp/reports/rn05.htm
13-Lang AE, Lozano AM. Parkinson's disease. First of two parts. N Engl J Med 1998; 339(15): 1044-53.
14-Beck, A. T., Ward, C. H., Mendelson, M., Mock. G. & Erbaugh, J. (1961). An inventory for measuring depression. Archive of General Psychiatry, 4, 561–571.
15-Beck, A. T., Steer, R. A. & Brown, G. K. (1969). Manual for the Beck Depression Inventory–II. San Antonio, TX: Psychological Corporation.
16-mohamadkhani parvaneh.psych coordinates beckdepression scale inlarge sample in major depression disorder.special issue rehabilitation  inpsychiatric  disoeders.1386—8(29)p.80-86
17-Manteghi.level of express emotion &depresson and distrees instuntman partnars hospitalized in Psychiatry wards and rrelationship with rehospitalization.psychiatric health rudiment quarterly.1389-12(1).p(409-10)
 
18-Papapetropoulos S, Ellul J, Argyriou AA, Chroni E, Lekka NP. The effect of depression on motor function and disease severity of parkinson’s disease. Clin Neurol Neurosurg. 2006;108(5):465-469.
19-Chaudhuri KR, Yates L, Martinez-Martin P. The non-motor symptom complex of Parkinson's disease: A comprehensive assessment is essential. Current Neurology and Neuroscience Reports. 2005; 5(4):275-83.
20-Stutts, L.A., Speight, K.L., Yoo, S. et al. Positive Psychological Predictors of Psychological Health in Individuals with Parkinson’s Disease. J Clin Psychol Med Settings 27, 182–189 (2020). https://doi.org/10.1007/s10880-019-09633-3
21-Zhang T. Y Shu-yang . Nonmotor symptoms in patients with Parkinson disease . Medicine: December 2016 - Volume 95 - Issue 50 - p e5400.
22-Farabaugh A, Joseph J, Yap L, Weintraub D, McDonald M, Agoston M, Alpert J, Growdon J, Fava M. Pattern of Depressive Symptoms in Parkinson’s Disease. Psychosomatics 2009; 50:448 – 454.
23-Hosseini SH, Yaghoobi H, Mobin M. Analysing Axis One Psychiatric Disorders in Fibromyalgia Patients. J Mazandaran Univ Med Sci 2015; 24(122): 348-353 .
24-Patel SR, Makani R, Mansuri Z, Patel U, Desai R, Chopra A. Impact of Depression on Hospitalization and Related Outcomes for Parkinson'sDisease Patients: A Nationwide Inpatient Sample-Based Retrospective Study. Cureus 9(9): e1648. DOI 10.7759/cureus.1648.
25-Hemmerle .AM,Herman.GP, Seroogy.KB. Experimental Neurology, 06 Oct 2011, 233(1):79-86.DOI: 10.1016/j.expneurol.2011.09.035.
26-Albert F.G. Leentjens, Anja J.H. Moonen, Kathy Dujardin, Laura Marsh, Pablo Martinez-Martin, Irene H. Richard, Sergio E. Starkstein, Sebastian Köhler ,First published August 14, 2013. vol. 81 no. 12 1036-1043.
27-Kim Y, Cheon SM, Youm C, Son M, Kim JW. Depression and posture in patients with Parkinson’s disease.Gait & Posture 61 2018; 81–85.
28-A.Rojo,M.Aguilar,M.T.Garolera,E.Cubo,I.Navas,S.Quintana. Depression in Parkinson's disease: clinical correlates and outcome.  Parkinsonism & Related Disorders.Volume 10, Issue 1, October 2003, Pages 23-28.