Oral Manifestations of Hematologic Malignancies

Document Type : Review

Authors

1 Assistant Professor of Oral and Maxillofacial Diseases.

2 Assistant Professor of Oral and Maxillofacial Diseases

3 Assistant Professor of Children's Oncology.

4 Department of Oral and Maxillofacial Diseases, Faculty of Dentistry, Islamic Azad University, Tehran, Iran.

Abstract

Background and Objectives: Hematologic malignancies are caused by impaired proliferation of blood cells. These diseases like some other systemic disorders have some manifestations in the oral cavity. The purpose of this study is to review the literature on oral signs and symptoms of malignant hematologic disorders in order to familiarize the dentists with these manifestations and assisting in early detection of the diseases.
Subjects and Methods: This study is based on a review of oral manifestations of hematological malignancies on reliable scientific databases. In this study “Oral manifestation”, “Lymphoma”, “Leukemia” and “Multiple myeloma” (single or double) were employed as keywords.
Results: Several papers on oral manifestations of hematologic malignancies (including leukemia, lymphoma and multiple myeloma) are available. Their results show that the oral signs and symptoms caused by these malignancies (e.g. pallor of the mucosa, gingival enlargement, bleeding, trismus, and bone changes) can be important evidence in identifying them and even in some cases may be the first sign of illness.
Conclusions: Oral signs and symptoms can be seen in a variety of hematologic malignancies, which even in some cases are the first signs of disease. So the dentist can play an important role in early detection and referral of patients to the relevant specialists.
 

Keywords

References

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Or
Jundishapur Scientific Medical Journal
Volume 14, Issue 4 - Serial Number 97
May and June 2015
Pages 478-485

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History

  • Receive Date: 22 October 2014
  • Revise Date: 05 May 2015
  • Accept Date: 20 June 2015

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