Background and aim: Preeclampsia disorder is a multi-systemic disorder characterized by hypertension and protein deficiency in the second half of pregnancy. because of the probability of increased thyroid dysfunction in mothers with preeclampsia, this study evaluated the thyroid dysfunction in patients with preeclampsia.
Materials and Methods: This study was a cross-sectional study that included 79 women with preeclampsia and 79 healthy pregnant women admitted to Imam Khomeini Hospital. For statistical analysis, we used the SPSS version 15 soft‌ware. Chi-square or Fisher exact and t tests were per-formed for evaluation of various risk factors and compare with quantitative variables. Statistical significance in the study was considered at P value of <0.05.
Results: The mean age of the patient group was 28.4 ± 6.5 years and in the healthy group 29.3 ± 6 years. The mean gestational age was 258.8 ± 22.3 and 254.5 ± 22.7 in the control group. Analysis shows that there is no significant difference between the levels of thyroid hormones in the two groups. In the statistical analysis of patients with normal pregnancy and preeclampsia for Anti TPO, anti-TPO levels were shown to be significantly higher in preeclampsia patients (P value <0.001).
Conclusion: this study shows that the incidence of preeclampsia can exacerbate the level of thyroid disorders, but this does not seem to be significant. Therefore, mothers who are at risk for preeclampsia should be monitored for thyroid function and should be treated appropriately if necessary, in order to prevent the exacerbation of this dangerous condition.