Document Type : Original Article
Authors
1
Department of Microbiology (M.sc), Islamic Azad University, Varamin- Pishva Branch, Varamin, Iran.
2
Assistant Professor, Department of Nursing, College of Nursing, Varamin- Pishva Branch, Islamic Azad University, Varamin, Iran.
3
Assistant Professor, Department of Nursing, College of Nursing, Varamin- Pishva Branch, Islamic Azad University, Varamin, Iran
10.22118/jsmj.2018.237003
Abstract
Background and Aims:
Different microorganisms can cause urinary tract infections, but Enterobacteriaceae family, like Escherichia coli and Klebsiella, are the most causative agents of urinary tract infections. So, in this study drug susceptibility testing of Klebsiella pneumonia and Escherichia coli (E.coli) was done to five common antibiotics.
Materials and Method:
This cross – sectional study was done on 100 samples ( 50 samples Klebsiella, 50 samples E.coli) isolated from patients with urinary infections (81 female , 19 male) with mean range 43.3±18.15 which biochemical separating tests and gram staining was done for accurate identification of strains. Antibiotic susceptibility test was done by disk diffusion (Kirby bauer) and microdilution method in accordance with CLSI M7 guideline. Obtained data were analyzed by SPSS software 17 and values of P < 0.05 were considered significant.
Results:
From 50 strains of E.coli, 45 strains to imipenem, 38 strains to ceftriaxone and ciprofloxacin, 18 strains to co- amoxiclav and 19 strains to co-trimoxazole were susceptible but from 50 strains of klebsiella, 45 strains to imipenem, 35 strains to ceftriaxone, 37 strains to ciprofloxacin, 20 strains to co- amoxiclav and 21 strains to co-trimoxazole were susceptible which results of both methods were conformed with each other.
Discussion:
With regard to increasing rate of antibiotic resistance, irregular and willfully use of antibiotics by patients should be controlled.
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