Jundishapur Journal of Medical Sciences

Jundishapur Journal of Medical Sciences

The Effect of Moderate Intensity Continuous Aerobic Training on Serum Spexin Level, Insulin Resistance and Body Composition in Inactive Obese Women

Document Type : Original Article

Authors
Maryam Salehi 1
Fahimeh Esfarjani 2
Sattar Gorgani Firoozjaei 3
1 PhD, Department of Exercise Physiology, Faculty of Physical Education and Sport Sciences, University of Isfahan, Isfahan, Iran.
2 Assistant Professor, Department of Sports Physiology, Faculty of Physical Education and Sport Sciences, University of Isfahan, Isfahan, Iran.
3 Assistant Professor, Department of Laboratory Sciences, Faculty of Paramedical Sciences, Aja University of Medical Sciences, Tehran, Iran.
10.32592/JSMJ.23.3.245
Abstract
Background and Objectives Spexin is a peptide related to energy homeostasis that affects pancreatic and insulin function. The aim of the present study was to determine the effect of moderate intensity continuous aerobic training on body composition, serum spexin and insulin resistance in inactive obese women.
Subjects and Methods In this quasi-experimental research, 24 inactive obese women were selected purposefully and were randomly divided into training (n=12) and control (n=12) groups. Participants engaged in a 10-week exercise program involving three weekly sessions of moderate-intensity continuous aerobic running. Body composition, insulin resistance and serum spexin levels were assessed under fasting conditions pre- and post-intervention. Statistical analysis involved paired sample t-tests and covariance analysis.
Results The training group demonstrated significant increases in serum spexin levels (P < 0.001, F = 43.678) and significant decreases in insulin resistance (P < 0.001, F = 30.542), body mass index (P < 0.001, F = 40.298), and waist circumference (P < 0.001, F = 384.939) compared to the control group.
Conclusion Moderate-intensity aerobic exercise decreased insulin resistance, possibly through improvements in body composition and increased serum spexin levels.
Keywords
Obesity
Aerobic training
Body combination
Spexin
Insulin resistance
Subjects

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Jundishapur Journal of Medical Sciences
Volume 23, Issue 3 - Serial Number 150
July and August 2024
Pages 245-254

  • Receive Date 10 March 2024
  • Revise Date 30 June 2024
  • Accept Date 30 June 2024