قابلیت MRS در افتراق ضایعات خوش خیم و بدخیم پروستات

نوع مقاله: مروری

نویسندگان

1 فیزیک پزشکی، دانشکده پزشکی ، دانشگاه علوم پزشکی جندی شاپور اهواز ، اهواز،ایران

2 دانشیار گروه فیزیک پزشکی ، دانشکده پزشکی ، دانشگاه علوم پزشکی جندی شاپور اهواز ، اهواز ، ایران.

3 استادیار گروه تکنولوژی پرتوشناسی ، دانشکده پیراپزشکی ، دانشگاه علوم پزشکی جندی شاپور اهواز ، اهواز ، ایران

4 استادیار گروه ارولوژی ، بیمارستان گلستان اهواز ، اهواز ، ایران .

5 استادیار گروه رادیولوژی ، بیمارستان گلستان اهواز ، اهواز ، ایران .

10.22118/jsmj.2018.148380.1460

چکیده

چکیده
هدف : با توجه به غیر تهاجمی بودن , حساسیت و اختصاص یافتگی طیف نگاری تشدید مغناطیسی و قابلیت آن در تشخیص ضایعات پروستات در مراحل ابتدایی ، هدف از مطالعه حاضر مرور سیستماتیک قابلیت این تکنیک در افتراق ضایعات خوش خیم و بدخیم پروستات می باشد .
مواد و روش ها: جستجوی مقالات در پایگاه های اطلاعاتی PubMed ، Science direct ، Embase ، Cochran و Scopus با استفاده از کلید واژه های MRS & prostate , prostate cancer , prostatitis , BPH و نیز Magnetic resonance Spectroscopyانجام شد .چکیده و متن کامل مقالات توسط نویسندگان بررسی شد و مطالعات مربوطه جهت مرور سیستماتیک انتخاب گردید .
نتایج: حساسیت ، اختصاص یافتگی و دقت MRS به میزان 74.03 % ، 74.27% و 77.26% در افتراق ضایعات خوش خیم و بدخیم پروستات بود . افزایش کولین و میواینوزیتول ، کاهش سیترات و پلی آمین و نسبت حاصل جمع بالاتر کولین و کراتین به سیترات در ضایعات بدخیم به عنوان نشان گرهای اصلی مطرح شده اند .
نتیجه گیری: MRS به عنوان یک روش غیر تهاجمی دارای حساسیت ، اختصاص یافتگی و دقت مطلوب در مقایسه با سایر روش های پاتولوژیک و بالینی می باشد .
واژگان کلیدی: MRS ، پروستات ، سرطان ، التهاب ، BPH .

کلیدواژه‌ها


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