کاربردهای زیست_ پزشکی کیتوزان با تأکید بر دارورسانی پوستی

نوع مقاله: مقاله پژوهشی

نویسندگان

1 مرکز تحقیقات فناوری نانو، دانشگاه علوم پزشکی جندی‌شاپور اهواز، ایران

2 مرکز تحقیقات فناوری نانو، دانشگاه علوم پزشکی جندی‌شاپور اهواز، ایران.

3 - مرکز تحقیقات فناوری نانو، دانشگاه علوم پزشکی جندی‌شاپور اهواز، ایران.

چکیده

دارورسانی پوستی به دلیل خصوصیات سدی لایۀ شاخی برای بسیاری از داروها دشوار است، اما با استفاده از حامل­های پلیمری از جمله کیتوزان می­توان میزان نفوذپذیری داروها را افزایش داد. کیتوزان یک بیوپلیمر طبیعی کاتیونیک غیرسمی است که به دلیل خصوصیات زیست سازگاری، زیست تخریب­پذیری، مخاط چسبی، آنتی­باکتریال و بند­آورندۀ خون، کاربردهای زیست_پزشکی زیادی از جمله ترمیم زخم و سوختگی دارد. این پلیمر می­تواند به عنوان سیستم دارورسان پوستی در سامانه­های دارویی مختلف مانند هیدروژل، فیلم و نانو ذره مورد استفاده قرار گیرد.
 

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